【摘要】：目的評價薇諾娜柔潤保濕霜對痤瘡的輔助治療作用。方法在根據(jù)病情酌情給予系統(tǒng)藥物治療的基礎(chǔ)上,將病人隨機分為治療組與對照組,治療組在系統(tǒng)用藥基礎(chǔ)上,外用薇諾娜柔潤保濕霜;對照組只進行系統(tǒng)用藥治療,不予以保濕霜處理,比較兩組在治療1周、2周、4周以后痤瘡綜合分級系統(tǒng)(GAGS)評分、痊愈率、有效率及皮膚生理功能(pH、角質(zhì)層含水量、油脂含量),以及停止治療4周后GAGS評分及皮膚生理功能。結(jié)果 1 200例納入病例,177例完成4周治療,停藥4周后155例獲得回訪;2治療1,2,4周后,兩組的GAGS評分均值較治療前均下降,治療組明顯低于對照組,前者痊愈率及有效率明顯高于后者(P0.05);兩組的pH值逐漸下降、角質(zhì)層含水量和油脂含量增加,治療組明顯好于對照組(P0.05);3治療結(jié)束后4周,治療組GAGS值明顯低于對照組(P0.05),pH值、角質(zhì)層含水量、油脂含量治療組也明顯好于對照組(P0.05)。以上差異均有統(tǒng)計學意義。結(jié)論在酌情采用藥物治療基礎(chǔ)上,薇諾娜柔潤保濕霜對于痤瘡的治療具有一定的輔助作用。
[Abstract]:Objective to evaluate the adjuvant effect of Winona moisturizing cream on acne. Methods patients were randomly divided into treatment group and control group on the basis of systemic drug therapy according to their condition. The treatment group was treated with Winona moisturizing cream on the basis of systemic medication. The patients in the control group were treated with systemic medication without moisturizing cream. The (GAGS) score, recovery rate, effective rate and skin physiological function (pH, corneum water content) of the acne comprehensive grading system were compared between the two groups after 1 week, 2 weeks and 4 weeks of treatment. Oil content, as well as GAGS score and skin physiological function after 4 weeks of cessation of treatment. Results among 1 200 cases, 177 cases were treated for 4 weeks, 155 cases received a return visit after 4 weeks. 2After 4 weeks of treatment, the mean GAGS score of the two groups was lower than that of the control group, and the cure rate and the effective rate of the former group were significantly higher than that of the latter group (P0.05). The pH value of the two groups decreased gradually and the water content and oil content of the cuticle increased significantly in the treatment group than in the control group (P0.05). 3 at 4 weeks after treatment, the GAGS value of the treatment group was significantly lower than that of the control group (P0.05), pH value, horny layer water content, oil content in the treatment group was also significantly better than that in the control group (P0.05). All the above differences were statistically significant. Conclusion on the basis of drug therapy, Winona moisturizing cream is helpful to the treatment of acne.
【作者單位】： 天津中醫(yī)藥研究院附屬醫(yī)院皮膚二科;
【分類號】：R758.733

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