【摘要】：目的:探索中國(guó)人群面部黑素細(xì)胞痣(melanocytic nevus,MN)皮膚鏡下常見(jiàn)的形態(tài)與年齡和面部部位的相關(guān)性。方法:用皮膚鏡記錄面部黑素細(xì)胞痣形態(tài),以年齡層、部位進(jìn)行分析比較。結(jié)果:假網(wǎng)狀、球狀、鵝卵石狀、中央網(wǎng)狀或均質(zhì)狀伴周?chē)驙?mixed reticular/homogeneous nevi with peripheral globules,MP)、混合型的不同年齡層組間差異有統(tǒng)計(jì)學(xué)意義(P0.05),除鵝卵石狀數(shù)量隨年齡增長(zhǎng)呈正相關(guān)性(P0.05),其余上述形態(tài)的數(shù)量隨年齡增長(zhǎng)均呈負(fù)相關(guān)性(P0.05)。各年齡層均以假網(wǎng)狀最多;球狀只出現(xiàn)在45歲組;鵝卵石狀在16歲組才能觀察到;MP及混合型只在30歲組。假網(wǎng)狀、鵝卵石狀、圈狀在各部位分布差異有統(tǒng)計(jì)學(xué)意義(P0.05),上述形態(tài)在各部位比例高低如下,假網(wǎng)狀:兩頰口周額頭鼻;鵝卵石狀:兩頰口周鼻子額頭;圈狀:兩頰鼻部額頭口周。首次提出圈狀應(yīng)為MN的形態(tài)之一。該研究未觀察到中央球狀或均質(zhì)狀伴周?chē)W(wǎng)狀(mix reticular nevi with central globules/homogeneous areas,MC)。結(jié)論:面部MN隨年齡增長(zhǎng),假網(wǎng)狀減少,球狀及鵝卵石狀總和增加,該研究可論證Nevogenisis的Abtropfung理論及內(nèi)外源性途徑。20歲有MP、MC、混合型特別是伴MN增大的患者應(yīng)定期隨訪。鵝卵石狀分布部位與Blaschko線基本符合;圈狀與毛孔好發(fā)部位符合。
[Abstract]:Objective: to explore the relationship between age and facial site of facial melanocytic nevus (melanocytic nevus,MN) in Chinese population. Methods: the morphology of facial nevus of melanocytes was recorded by dermatoscope. Results: pseudo-reticular, globular, cobblestone, Central reticular or homogeneous with peripheral globular (mixed reticular/homogeneous nevi with peripheral globules,MP), there were significant differences among different age groups of mixed type (P0.05). The number of cobblestones was positively correlated with age (P0.05), and the number of other forms increased with age (P0.05). The length was negatively correlated (P0.05). False reticulation was the most common in all age groups; globular appearance was found only in 45 years old group; cobblestone was observed only in 16 years old group and mixed type was found only in 30 years old group. The distribution of pseudo-reticular, cobblestone and cobblestone was statistically significant (P0.05). The proportion of the above shape in each part was as follows: pseudo-reticular: frontal nose around two buccal orifice, cobblestone: nose forehead around buccal orifice; Circle-like: around the forehead and mouth of both cheeks and nostrils. For the first time, it was suggested that the ring shape should be one of the forms of MN. No central globular or homogeneous (mix reticular nevi with central globules/homogeneous areas,MC was observed in this study. Conclusion: facial MN increases with age, pseudo-reticular decrease, globular and cobblestone summation. This study can demonstrate the Abtropfung theory of Nevogenisis and the internal and external pathway. 20 years old patients with mixed MP,MC, especially with increased MN, should be followed up regularly. The distribution of cobblestone was basically consistent with Blaschko line, and that of circle and pore was consistent.
【作者單位】： 廈門(mén)長(zhǎng)庚醫(yī)院皮膚科;上海復(fù)旦大學(xué)附屬華山醫(yī)院皮膚科;
【分類(lèi)號(hào)】：R758.51

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