本文選題：快速血漿反應(yīng)素試驗 + 時間分辨熒光免疫法�。� 參考：《中國皮膚性病學(xué)雜志》2014年11期

【摘要】：目的探討梅毒患者抗體與年齡、性別、療程以及不同臨床分期的關(guān)系,為臨床合理化治療提供參考。方法 243例梅毒患者采用時間分辨熒光免疫法(TRFIA)檢測梅毒螺旋體抗體含量,用快速血漿反應(yīng)素試驗(RPR)檢測血清中反應(yīng)素滴度,TRFIA陽性患者用梅毒螺旋體明膠顆粒凝集試驗(TPPA)確認(rèn)。結(jié)果梅毒螺旋體特異性抗體的含量各年齡組相互比較差異有統(tǒng)計學(xué)意義(P0.01),不同性別間其含量差異無統(tǒng)計學(xué)意義(P0.05),恢復(fù)期患者梅毒螺旋體特異性抗體的含量顯著高于治療初期(P0.01);RPR≥1∶8患者的數(shù)量在19~29歲的人群中所占比例最高(53.06%),其次是胎傳梅毒占41.56%,治療1個月RPR陰轉(zhuǎn)率(6.52%)與三個月的陰轉(zhuǎn)率(16.30%)相比,差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論梅毒抗體在不同人群、不同治療階段以及不同臨床分期中各不相同,在隱性梅毒患者中孕產(chǎn)婦數(shù)量較多,應(yīng)加強對孕產(chǎn)婦梅毒患者的治療和健康教育工作,減少胎傳梅毒的發(fā)生率。
[Abstract]:Objective to study the relationship between antibody and age, sex, course of treatment and different clinical stages in syphilis patients, so as to provide reference for rational treatment of syphilis. Methods the levels of Treponema pallidum antibody were detected by time resolved fluorescence immunoassay (TRFIA) in 243 patients with syphilis, and the serum levels of Reagin titer and TRFIA were detected by rapid plasma reactive hormone test (RPRP). TPPAs were confirmed by Treponema pallidum gelatin particle agglutination test (TPPA) in 243 patients with syphilis. Results the content of specific antibody to Treponema pallidum was significantly different among different age groups (P 0.01). There was no significant difference in the content of Treponema pallidum in different sex. The content of specific antibody of Treponema pallidum in convalescent patients was significantly higher. In the early stage of treatment, the number of patients with RPR 鈮，

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