硒蛋白功能與特應(yīng)性皮炎的關(guān)系研究進(jìn)展
發(fā)布時(shí)間:2018-03-28 02:24
本文選題:硒 切入點(diǎn):硒蛋白 出處:《臨床皮膚科雜志》2014年03期
【摘要】:特應(yīng)性皮炎(AD)是一種慢性復(fù)發(fā)性炎癥反應(yīng)。AD的發(fā)病過程伴有氧化應(yīng)激水平升高,Th1/Th2失衡,調(diào)節(jié)性T細(xì)胞(Tregs)和胸腺基質(zhì)淋巴細(xì)胞生成素(TSLP)表達(dá)異常等特征。硒是人體必需的微量營養(yǎng)素。膳食硒在人體通過硒蛋白發(fā)揮生物效應(yīng)。硒蛋白可能通過抗氧化防御、氧化還原信號(hào)調(diào)控和免疫反應(yīng)調(diào)節(jié)等生物學(xué)功能在AD中發(fā)揮作用。
[Abstract]:Atopic dermatitis (AD) is a chronic recurrent inflammatory response. AD is associated with increased oxidative stress levels and Th1 / Th2 imbalance. Selenium is a necessary micronutrient in human body. Dietary selenium plays a biological role in human body through selenium protein. Selenin may be through antioxidant defense. Biological functions such as redox signal regulation and immune response regulation play an important role in AD.
【作者單位】: 深圳市慢性病防治中心;
【基金】:國家自然科學(xué)基金(81172669)資助項(xiàng)目
【分類號(hào)】:R758.23
【共引文獻(xiàn)】
相關(guān)期刊論文 前3條
1 Liana Manolache;Dana Petrescu-Seceleanu;;Stress involvement as trigger factor in different skin conditions[J];World Journal of Dermatology;2013年03期
2 李頌;衣U,
本文編號(hào):1674349
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