3例陰莖透明細胞癌:一種與HPV相關的鱗狀細胞癌變異亞型的報道
發(fā)布時間:2019-08-03 17:56
【摘要】:正目前文獻報道的陰莖透明細胞癌起源于皮膚附屬器的腺體。作者介紹了3例形態(tài)學獨特的陰莖腫瘤,該腫瘤具有明顯的透明細胞特點,但并非起源于陰莖皮膚,而是起源于龜頭表面鱗狀上皮的黏膜組織。作者對其臨床及病理學特征進行分析。免疫組化檢測GATA3及p16的表達。采用原位雜交法檢測3例陰莖透明細胞癌的HPV表達情況,其中1例全組織切片進行聚合酶鏈反應。患者年齡分別為52、88
[Abstract]:Clear cell carcinoma of the penis, as reported in the literature, originates from the gland of the skin appendage. Three cases of penile tumors with unique morphology were introduced. The tumor has obvious clear cell characteristics, but does not originate from penile skin, but from the mucous tissue of scaly epithelial tissue on the surface of glans. The clinical and pathological features were analyzed. The expression of GATA3 and p16 was detected by immunohistochemistry. The expression of HPV in 3 cases of clear cell carcinoma of penis was detected by in situ hybridization, and 1 case of whole tissue section was detected by polymerase chain reaction (PCR). The ages of the patients were 52 and 88 respectively.
【作者單位】: 浙江省紹興市人民醫(yī)院病理科;解放軍307醫(yī)院病理科;
【分類號】:R737.27
[Abstract]:Clear cell carcinoma of the penis, as reported in the literature, originates from the gland of the skin appendage. Three cases of penile tumors with unique morphology were introduced. The tumor has obvious clear cell characteristics, but does not originate from penile skin, but from the mucous tissue of scaly epithelial tissue on the surface of glans. The clinical and pathological features were analyzed. The expression of GATA3 and p16 was detected by immunohistochemistry. The expression of HPV in 3 cases of clear cell carcinoma of penis was detected by in situ hybridization, and 1 case of whole tissue section was detected by polymerase chain reaction (PCR). The ages of the patients were 52 and 88 respectively.
【作者單位】: 浙江省紹興市人民醫(yī)院病理科;解放軍307醫(yī)院病理科;
【分類號】:R737.27
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1 向梅;;透明細胞癌的手術治療[J];國外醫(yī)學.婦產科學分冊;2006年03期
2 林R,
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