【摘要】：正腎間質(zhì)纖維化是幾乎每種類(lèi)型的慢性腎病不可避免的后果,然而其潛在機(jī)制尚未完全清楚。Tian等在既往的研究中確定,表面活性蛋白A(surfactant protein A,SP-A)是參與單側(cè)輸尿管梗阻(unilateral ureter obstruction,UUO)誘導(dǎo)的腎纖維化的一種新的蛋白因子。UUO誘導(dǎo)小鼠腎上皮中SP-A表達(dá),可能是由于增加的酸性應(yīng)激和炎癥。有趣的是,SP-A缺乏加重UUO
[Abstract]:Positive renal interstitial fibrosis is an inevitable consequence of almost every type of chronic kidney disease, but its potential mechanism is not fully understood. Tian et al., in previous studies, determined that A (surfactant protein A, SP 鈮，

本文編號(hào)：2520220