【摘要】：目的探討輸尿管腎源性腺瘤(nephrogenic adenoma,NA)的臨床病理學和免疫表型特征。方法回顧性分析1例輸尿管NA合并腎臟結核的臨床資料及病理學特征,對其行HE及免疫組化En Vision法染色,并復習相關文獻。結果患者男性,18歲。大體上輸尿管腔內見狹窄區(qū);鏡下見黏膜下增生腺體形成小管狀、乳頭狀結構,管腔大小形狀不一,被覆單層立方上皮,黏膜下見慢性炎細胞浸潤;腎臟結核改變。免疫表型:AMACR(P504s)(+);CK7(弱+);CK34βE12(局灶+);CD10、CK20、Villin、vimentin(-)。結論輸尿管NA是非常少見的泌尿系統(tǒng)病變,需與息肉、移行細胞癌及腺癌鑒別,掌握其組織形態(tài)特征及免疫表型是正確診斷的關鍵。
[Abstract]:Objective to investigate the clinicopathological and immunophenotypic features of ureteral renal adenoma (nephrogenic adenoma,NA). Methods A case of ureteral NA complicated with renal tuberculosis was retrospectively analyzed. HE and immunohistochemical En Vision staining were performed. Results the patient was 18 years old. In general, the stricture area was seen in ureteral lumen. Under the microscope, there were small tubules, papillary structure, different shape of lumen, single layer cubic epithelium, chronic inflammatory cell infiltration in submucous membrane, and the change of renal tuberculosis. Immunophenotype: AMACR (P504s) (); CK7 (weak); CK34 尾 E12 (focal); CD10,CK20,Villin,vimentin (-). Conclusion Ureteral NA is a rare urinary system disease. It is necessary to differentiate ureteral NA from polyps, transitional cell carcinoma and adenocarcinoma. It is the key to correct diagnosis to master the histological features and immunophenotypes of ureteral NA.
【作者單位】： 山東省聊城市第二人民醫(yī)院病理科;
【分類號】：R527.1;R737.13
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本文編號：2268025