本文關(guān)鍵詞：泌尿系感染患者病原菌分布及藥物敏感性分析，由筆耕文化傳播整理發(fā)布。

泌尿系感染患者病原菌分布及藥物敏感性分析

Analysis of drug sensitivity and distribution of pathogens in patients with urinary tract infections

[1] [2] [3] [4]

YUAN Shuqiao, BAN Lisu, ZHAO Qiang, ZHANG Liwen（ 1Department of Clinical Laboratory, the First Affiliated Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China;

[1]蘭州大學(xué)第一醫(yī)院檢驗(yàn)科,甘肅蘭州730000; [2]河北省武安市婦幼保健院,河北武安056300; [3]解放軍總醫(yī)院,北京100853

文章摘要：目的分析泌尿系感染患者病原菌的分布及藥物敏感性特征,為臨床泌尿系感染的治療提供依據(jù)。方法對(duì)2014年1-12月就診于解放軍總醫(yī)院腎病科門診的953例泌尿系感染患者的953份尿標(biāo)本同時(shí)進(jìn)行支原體、細(xì)菌培養(yǎng)鑒定和藥物敏感性試驗(yàn)。結(jié)果953例泌尿系感染患者中,395例支原體培養(yǎng)陽(yáng)性,陽(yáng)性檢出率41.45%,對(duì)美滿霉素和強(qiáng)力霉素敏感率〉90%;154例細(xì)菌培養(yǎng)陽(yáng)性,陽(yáng)性檢出率16.16%,分離菌株156株,大腸埃希菌71株占首位,其次為草綠色鏈球菌14株、糞腸球菌12株、肺炎克雷伯菌11株、無(wú)乳鏈球菌11株等,大腸埃希菌和肺炎克雷伯菌超廣譜β-內(nèi)酞胺酶陽(yáng)性率分別為45.07%和18.18%,未發(fā)現(xiàn)對(duì)亞胺培南、美羅培南耐藥的大腸埃希菌和肺炎克雷伯菌,以及對(duì)萬(wàn)古霉素、利奈唑胺耐藥的草綠色鏈球菌、糞腸球菌和無(wú)乳鏈球菌。結(jié)論泌尿系感染患者病原菌以解脲支原體和大腸埃希菌為主,及時(shí)監(jiān)測(cè)病原菌的種類分布及藥物敏感性特征,對(duì)泌尿系感染疾病的治療有重要意義。

Abstr：Objective To analyze the drug sensitivity and distribution of pathogens in patients with urinary tract infections, and provide basis for clinical treatment of urinary tract infection. Methods From January 2014 to December 2014, the identification and drug sensitivity testing were performed simultaneously for Mycoplasma and bacteria were isolated from urine specimens that were obtained from the outpatients of nephropathy department. Results Of the 953 patients with urinary tract infection, 395 cases were positive in mycoplasma culture, with the positive rate of 41.45% and the susceptibility rate of more than 90% to Doxycycline and Minocycline; 154 cases were positive in bacterial culture, with the positive rate of 16.16%; 156 strains were isolated, and Escherichia coli was the main pathogen （71 strains, accounting for 45.51%）, followed by Streptococcus viridans （14 strains, 8.97%）, Enterococcus （12 strains, 7.69%）, Klebsiella pneumonia （11 strains, 7.05%）, Streptococcus agalactiae （11 strains, 7.05%）. ESBL positive rates of Escherichia coli and Klebsiella pneumonia were 45.07% and 18.18%, respectively. No strains of Escherichia coli and Klebsiella pneumonia were found resistant to Imipenem or Meropenem, and no strains of Streptococcus viridans, Enterococcus, Streptococcus agalactiae were found resistant to Vancomycin or Linezolid. Conclusion Mycoplasma urealytium and Escherichia coli are the main pathogens in patients with urinary tract infection. Monitoring of species distribution and drug sensitivity characteristics of pathogens is important for the treatment of urinary infection diseases.

文章關(guān)鍵詞：

Keyword：:urinary tract infection pathogen drug susceptibility anti-bacterial agents

  本文關(guān)鍵詞：泌尿系感染患者病原菌分布及藥物敏感性分析，由筆耕文化傳播整理發(fā)布。