本文選題：腎透析 + 腎疾病�。� 參考：《福建醫(yī)科大學(xué)學(xué)報》2015年06期

【摘要】：目的了解福建省閩西地區(qū)終末期腎病(ESRD)患者的病因構(gòu)成及其貧血狀況。方法回顧性分析閩西地區(qū)11家醫(yī)院2014年1-12月因ESRD行維持性血液透析的858例患者的臨床資料,比較患者的血紅蛋白水平與鐵缺乏、營養(yǎng)狀況、甲狀旁腺激素、透析充分性、促紅細(xì)胞生成素(EPO)治療之間的關(guān)系。結(jié)果 ESRD的病因中,前3位分別為慢性腎小球腎炎(458例,52.79%)、糖尿病腎病(143例,16.67%)和高血壓腎病(128例,14.92%)。使用EPO治療775例,治療率90.33%,貧血治療達(dá)標(biāo)率42.87%。血紅蛋白越低,EPO治療的比例越高,用量也越大。與貧血治療達(dá)標(biāo)患者比較,貧血治療不達(dá)標(biāo)患者血清鐵蛋白、轉(zhuǎn)鐵蛋白飽和度、血清白蛋白水平明顯低下(均為P0.05),血甲狀旁腺素、肌酐、尿素氮水平明顯升高(均為P0.05),每周3次透析的患者所占比例明顯下降(P0.05)。結(jié)論閩西地區(qū)ESRD的病因主要是原發(fā)性腎小球腎炎、糖尿病腎病和高血壓腎損害;維持性血液透析患者貧血治療率高,但達(dá)標(biāo)率仍偏低,主要影響因素是鐵缺乏、營養(yǎng)不良、繼發(fā)性甲狀旁腺功能亢進和透析不充分。
[Abstract]:Objective to investigate the etiology and anemia of patients with end-stage renal disease (ESRD) in western Fujian province. Methods the clinical data of 858 patients undergoing ESRD maintenance hemodialysis in 11 hospitals in western Fujian from January to December 2014 were analyzed retrospectively. The hemoglobin levels, iron deficiency, nutritional status, parathyroid hormone and dialysis adequacy were compared. The relationship between EPO and EPO treatment. Results among the etiology of ESRD, the first three were chronic glomerulonephritis in 458 cases (52.79), diabetic nephropathy in 143 cases (16. 67) and hypertensive nephropathy in 128 cases (14. 92%). 775 cases were treated with EPO, the treatment rate was 90.33 and the rate of anemia was 42.87. The lower the hemoglobin, the higher the proportion and dosage of EPO. The levels of serum ferritin, transferrin saturation and serum albumin were significantly lower in patients with anemia than in patients with anemia who did not meet the standard of treatment (all P 0.05, serum parathyroid hormone, creatinine, serum parathyroid hormone, creatinine). The level of urea nitrogen increased significantly (all P 0.05), and the proportion of patients who received dialysis three times a week decreased significantly (P 0.05). Conclusion the main causes of ESRD in western Fujian are primary glomerulonephritis, diabetic nephropathy and hypertensive renal damage, the rate of anemia treatment in maintenance hemodialysis patients is high, but the rate of reaching the standard is still low, the main influencing factors are iron deficiency and malnutrition. Secondary hyperparathyroidism and inadequate dialysis.
【作者單位】： 福建醫(yī)科大學(xué)附屬龍巖市第一醫(yī)院腎內(nèi)科;
【分類號】：R692.5

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