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經(jīng)尿道等離子切除與傳統(tǒng)電切術治療膀胱腫瘤的meta分析

發(fā)布時間:2018-04-30 10:36

  本文選題:等離子切除 + 膀胱腫瘤。 參考:《重慶醫(yī)科大學》2014年碩士論文


【摘要】:目的研究與傳統(tǒng)電切(TURBT)治療膀胱腫瘤相比,經(jīng)尿道等離子切除(PKRBT)在臨床使用中的優(yōu)點和缺點,為以后臨床決策及研究提供客觀的依據(jù)。 方法通過計算機檢索1993年-2013年Pubmed、EMbase、Cochrane圖書館、CNKI、中國生物醫(yī)學文獻數(shù)據(jù)庫、維普數(shù)據(jù)庫等,通過手工檢索輔助完整的收集相關文獻,搜索內容為所有涉及比較經(jīng)尿道等離子切除與傳統(tǒng)電切術處理膀胱腫瘤的隨機對照試驗,按照納入與排除標準選擇合適文獻,通過資料提取和質量評價后其中7篇符合等離子切除術與經(jīng)尿道電切術的隨機對照研究(RCTs),,應用Reman5.0軟件進行數(shù)據(jù)處理和分析。 結果對成功納入的符合標準的7篇文獻,統(tǒng)計共有643例患者,進行meta分析后得出結果如下:1.手術時間比較兩組無明顯差異[WMD=-0.89,95%CI(-2.77,0.99),P=0.35];2.術中出血量比較兩組無明顯差異[WMD=-6.79,95%CI(-16.12,2.55),P=0.15];3.手術并發(fā)癥比較等離子切除術低于傳統(tǒng)經(jīng)尿道電切術[RR=0.31,95%CI(0.21,0.48),P0.00001];4.術后復發(fā)率等離子切除術低于傳統(tǒng)經(jīng)尿道電切術[RR=0.70,95%CI(0.53,0.92),P0.001]。 結論與傳統(tǒng)經(jīng)尿道電切術治療淺表性膀胱癌相比,經(jīng)尿道等離子切除術更安全有效,能降低手術并發(fā)癥及術后2年內的復發(fā)率。
[Abstract]:Objective to study the advantages and disadvantages of transurethral resection of PKRBT in the treatment of bladder neoplasms compared with traditional TURBT, and to provide an objective basis for future clinical decision making and research. Methods CNKI, China Biomedical Literature Database and Wiper Database were searched by computer from 1993 to 2013 in the Pubmedus EMbase Cochrane Library. The relevant documents were collected by manual retrieval. All randomized controlled trials involving the comparison of transurethral plasma resection and conventional electroresection of bladder tumors were conducted, and appropriate literature was selected according to the inclusion and exclusion criteria. After data extraction and quality evaluation, seven of them were randomly compared with plasma resection and transurethral resection. The data were processed and analyzed by Reman5.0 software. Results A total of 643 patients were included successfully in 7 articles that met the criteria. The results of meta analysis were as follows: 1. 1. There was no significant difference in operation time between the two groups. There was no significant difference in intraoperative blood loss between the two groups [WMD-6.79N95, CI-16.122.55P0. 15]. Compared with conventional transurethral resection, the complications of operation were lower than that of conventional transurethral resection. The recurrence rate of plasma resection was lower than that of traditional transurethral resection. Conclusion compared with traditional transurethral resection, transurethral plasma resection is more safe and effective in the treatment of superficial bladder cancer, and can reduce the postoperative complications and recurrence rate within 2 years.
【學位授予單位】:重慶醫(yī)科大學
【學位級別】:碩士
【學位授予年份】:2014
【分類號】:R737.14

【參考文獻】

相關期刊論文 前4條

1 周青;陳耀武;舒暢;王原;曾志;鄒政;朱云海;朱江;;經(jīng)尿道膀胱腫瘤電切術與等離子切除術的對比研究[J];臨床泌尿外科雜志;2010年02期

2 諶惠明;劉斌;陳兵海;;腹腔鏡行根治性膀胱切除術安全性及有效性的meta分析[J];湖南師范大學學報(醫(yī)學版);2013年02期

3 陳偉;薄雋杰;張連華;沙建軍;張慧國;劉東明;黃翼然;;經(jīng)尿道鈥激光治療淺表性膀胱腫瘤的臨床分析——附92例報告[J];中國癌癥雜志;2009年03期

4 吳剛;谷寶軍;;經(jīng)尿道鈥激光治療淺表性膀胱腫瘤效果的Meta分析[J];中國循證醫(yī)學雜志;2011年05期



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