非阿片藥物復合推管內(nèi)麻醉在大腸癌手術中使用的可行性研究
發(fā)布時間:2019-08-06 12:51
【摘要】:目的分析非阿片藥物復合推管內(nèi)麻醉在大腸癌手術中使用的可能性。方法將75例各類(腔鏡和開腹)大腸癌手術的患者分為阿片藥物麻醉(A組)、阿片藥物復合椎管內(nèi)麻醉(H組)、非阿片藥物復合椎管內(nèi)麻醉(F組)3組。記錄不同階段的熵指數(shù)、心率(HR)、平均動脈壓(MAP)、蘇醒時間、拔管時間、患者術前和術后各時間點疼痛的VAS評分、術后肛門排氣時間;術后住院時間;并采用ELISA測試血清干擾素-γ(INF-γ)及白細胞介素(IL)-6、IL-10的水平。結果 3組患者麻醉時的熵指數(shù)、HR及MAP比較差異無統(tǒng)計學意義(P0.05);F組患者的蘇醒時間、拔管時間與A、H組比較,差異有統(tǒng)計學意義(P0.05);H、F組患者的VAS評分顯著低于A組(P0.05),但H、F組比較差異無統(tǒng)計學意義(P0.05);3組患者術后肛門排氣時間與住院時間比較差異無統(tǒng)計學意義(P0.05);手術3d后,H、F組患者的IFN-γ水平高于A組(P0.05),但H、F組比較差異無統(tǒng)計學意義(P0.05);手術1d后,A組患者的IL-6水平高于H、F組(P0.05),但H、F組比較差異無統(tǒng)計學意義(P0.05);手術完畢時,A組患者的IL-10水平明顯高于H、F組(P0.05),但H、F組比較差異無統(tǒng)計學意義(P0.05)。結論基于樣本分析結果,非阿片藥物復合椎管內(nèi)麻醉對大腸癌手術患者可能有更好的保護作用,對患者的術后恢復有更好的促進作用。
[Abstract]:Objective to analyze the possibility of non-opioid combined tubule anesthesia in colorectal cancer surgery. Methods 75 patients undergoing colorectal cancer surgery were divided into three groups: opioid anesthesia (group A), opioid combined with intraspinal anesthesia (group H) and non-opioid combined with intraspinal anesthesia (group F). Entropy index, heart rate (HR), mean arterial pressure (MAP), recovery time, extubation time, VAS score of pain before and after operation, postoperative anal exhaust time, postoperative hospitalization time, serum interferon-gamma (INF- 緯) and IL-6, IL 鈮,
本文編號:2523557
[Abstract]:Objective to analyze the possibility of non-opioid combined tubule anesthesia in colorectal cancer surgery. Methods 75 patients undergoing colorectal cancer surgery were divided into three groups: opioid anesthesia (group A), opioid combined with intraspinal anesthesia (group H) and non-opioid combined with intraspinal anesthesia (group F). Entropy index, heart rate (HR), mean arterial pressure (MAP), recovery time, extubation time, VAS score of pain before and after operation, postoperative anal exhaust time, postoperative hospitalization time, serum interferon-gamma (INF- 緯) and IL-6, IL 鈮,
本文編號:2523557
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