【摘要】：目的觀察靜脈注射布托啡諾聯(lián)合腹腔內(nèi)注射羅哌卡因?qū)D科腹腔鏡手術(shù)患者術(shù)后疼痛的影響。方法將2013年9月~2014年3月80例擇期在全身麻醉下行婦科腹腔鏡手術(shù)患者隨機分為觀察組(羅哌卡因聯(lián)合布托啡諾組)和對照組,每組40例。觀察組術(shù)前30分鐘靜脈注射布托啡諾20μg/kg,并在氣腹結(jié)束前向手術(shù)創(chuàng)面噴灑0.4%羅哌卡因5 ml,縫合皮膚前向切口局部注射0.4%羅哌卡因5 ml。對照組給予同等量生理鹽水。采用視覺模擬評分(visual analogue score,VAS)評價術(shù)后2、6、12、24 h的疼痛強度。結(jié)果術(shù)后2、6、12 h觀察組的VAS均低于對照組(2 h:4.1±0.6 vs.6.8±0.8,t=-16.419,P=0.000;6 h:3.2±0.8 vs.7.1±1.5,t=-14.425,P=0.000;12 h:3.4±0.5 vs.6.2±1.9,t=-8.733,P=0.002),術(shù)后24 h 2組VAS差異無顯著性(3.1±0.8 vs.3.2±0.7,t=-0.723,P=0.472)。結(jié)論布托啡諾聯(lián)合羅哌卡因可顯著緩解婦科腹腔鏡術(shù)后疼痛,且無明顯不良反應(yīng)。
[Abstract]:Objective to observe the effect of intravenous butofenol combined with intraabdominal injection of ropivacaine on postoperative pain in patients undergoing gynecological laparoscopic surgery. Methods from September 2013 to March 2014, 80 patients undergoing gynecological laparoscopic surgery under general anesthesia were randomly divided into observation group (ropivacaine combined with butorphalin group) and control group (n = 40). In the observation group, 20 渭 g / kg, butofenol was injected intravenously 30 minutes before pneumoperitoneum and 0.4% ropivacaine was sprayed with 0.4% ropivacaine 5 ml, to suture the skin and local injection of 0.4% ropivacaine 5 ml. before pneumoperitoneum was completed. The control group was given the same amount of saline. Visual analog score (visual analogue score,VAS) was used to evaluate the pain intensity at 2 h, 6 h, 12 h and 24 h after operation. Results the VAS of the observation group was lower than that of the control group at 2 h, 6 h and 12 h after operation (4. 1 鹵0. 6 vs.6.8 鹵0.8, t = 16. 419, P < 0. 006 h, 3. 2 鹵0. 8 vs.7.1 鹵1. 5, t = 14. 425, P 鈮，

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