發(fā)布時間：2019-02-18 14:34

【摘要】：目的探討帕瑞昔布超前鎮(zhèn)痛對氣管插管全身麻醉患者麻醉效果的影響。方法將100例塵肺患者隨機(jī)分為帕瑞昔布組及對照組,每組50例。兩組均于氣管插管全麻下行大容量單肺灌洗術(shù)。帕瑞昔布組于誘導(dǎo)前20 min靜脈注射帕瑞昔布40 mg,對照組靜脈注射等量生理鹽水。比較兩組手術(shù)時間、術(shù)后蘇醒時間、蘇醒期平均動脈壓(MAP)、心率(HR)、動脈血氧飽和度(Sp O2)的變化及蘇醒期躁動發(fā)生率、術(shù)后24 h咽喉痛發(fā)生率。結(jié)果兩組手術(shù)時間、蘇醒時間差異均無統(tǒng)計(jì)學(xué)意義。帕瑞昔布組蘇醒期MAP、HR均低于對照組(P0.05),帕瑞昔布組蘇醒期躁動發(fā)生率及術(shù)后24 h咽喉痛發(fā)生率均低于對照組(P均0.05)。結(jié)論帕瑞昔布超前鎮(zhèn)痛可抑制全麻患者術(shù)后蘇醒期躁動,降低術(shù)后24 h咽喉痛的發(fā)生率。
[Abstract]:Objective to investigate the effect of preemptive analgesia with paroxib on the anesthetic effect of tracheal intubation general anesthesia. Methods 100 patients with pneumoconiosis were randomly divided into two groups: paroxib group and control group. Large volume single lung lavage was performed under tracheal intubation and general anesthesia in both groups. Paroxib group received paroxib 40 mg, intravenously 20 min before induction. The changes of mean arterial pressure (MAP), arterial oxygen saturation (Sp O 2), arterial oxygen saturation (Sp O 2) and arthralgia at 24 h after operation were compared between the two groups. Results there was no significant difference in operation time and recovery time between the two groups. The MAP,HR in the paroxib group was lower than that in the control group (P0.05), and the incidence of restlessness and larynx pain at 24 hours after operation in the paroxib group was lower than that in the control group (P0.05). Conclusion Paroxib preemptive analgesia can inhibit restlessness and reduce the incidence of pharynx and larynx pain 24 hours after operation in patients with general anesthesia.
【作者單位】： 三峽大學(xué)第一臨床醫(yī)學(xué)院;
【基金】：宜昌市科技局基金資助項(xiàng)目(A14-30323)
【分類號】：R614.2

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