小劑量甲氧明對剖宮產(chǎn)麻醉產(chǎn)婦血流動(dòng)力學(xué)和新生兒血?dú)獾挠绊?/H1>
發(fā)布時(shí)間：2018-12-16 19:03
【摘要】：目的探討小劑量甲氧明對剖宮產(chǎn)手術(shù)麻醉中產(chǎn)婦血流動(dòng)力學(xué)和新生兒的影響。方法選取2014年1月至2016年6月間在該院行剖宮產(chǎn)術(shù)實(shí)施腰-硬聯(lián)合麻醉產(chǎn)婦285例,分3組,A組麻醉完成后即刻靜脈注射鹽酸甲氧明1mg,B組注射2mg,C組靜脈注射生理鹽水2mL,記錄入室平靜后基礎(chǔ)值(T0)、麻醉平臥位即刻(T_1)、麻醉平臥后1min(T_2)、麻醉平臥后5min(T_3)、胎兒娩出前1min(T4)、胎兒娩出后5min(T5)各時(shí)間點(diǎn)產(chǎn)婦的收縮壓(SBP)、心率(HR)變化情況,新生兒臍動(dòng)脈血pH、血?dú)庵笜?biāo)[氧分壓(PO_2),二氧化碳分壓(PCO_2)]及出生1min Apgar評分,觀察產(chǎn)婦術(shù)中出現(xiàn)惡心、嘔吐等不良反應(yīng)情況。結(jié)果 B組及C組產(chǎn)婦在T_2時(shí)刻HR明顯升高后又明顯降低(P0.05),而A組產(chǎn)婦在T_1時(shí)刻開始降低后,在T_2~T4各時(shí)間點(diǎn)HR均明顯低于B組及C組,且無較大波動(dòng)(P0.05);3組產(chǎn)婦的SBP自T_2時(shí)刻起均較T0時(shí)刻明顯降低(P0.05),但在T_2~T4各時(shí)間點(diǎn)A組產(chǎn)婦的SBP均明顯高于B組及C組(P0.05);A、B組新生兒臍動(dòng)脈血pH、血?dú)庵笜?biāo)及出生1min后Apgar評分組間差異均無統(tǒng)計(jì)學(xué)意義(P0.05),但C組新生兒臍動(dòng)脈血pH、出生1min后Apgar評分均明顯低于A、B組(P0.05);A組產(chǎn)婦的不良反應(yīng)率為2.11%,明顯低于B組(9.47)%及C組(13.68)%,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論小劑量甲氧明能夠有效維持剖宮產(chǎn)術(shù)腰硬聯(lián)合麻醉后產(chǎn)婦血流動(dòng)力學(xué)平穩(wěn),對新生兒無不良影響。
[Abstract]:Objective to investigate the effect of low dose methoxifen on hemodynamics of parturient and newborn during cesarean section anesthesia. Methods from January 2014 to June 2016, 285 cases of parturient undergoing combined spinal-epidural anesthesia were divided into 3 groups. Group A received intravenous injection of methoxifen hydrochloride 1 mg / g immediately after anesthesia, and group B received 2 mg of methoxifen hydrochloride immediately after anesthesia. In group C, normal saline was injected intravenously for 2 mL. The baseline value (T _ 0), 1min (T _ 2), 1min (T _ 4) and 1min (T _ 4) before delivery of fetus were recorded in group C, respectively, and were recorded immediately after anaesthesia supine position (T _ 1), 1min (T _ 2) after anaesthesia supine and 5min (T _ s _ 3) after anaesthesia. The changes of systolic blood pressure (SBP),) heart rate (HR), blood gas index (PO_2), partial pressure of carbon dioxide (PCO_2) in umbilical artery of newborn and 1min Apgar score of birth were measured at different time points of 5min (T5) after delivery. The adverse reactions such as nausea and vomiting in parturient were observed. Results in group B and group C, HR increased significantly and then decreased (P0.05), but the HR in group A was significantly lower than that in group B and C at each time point after T _ 1 began to decrease. There was no significant fluctuation (P0.05). The SBP of parturient in group A was significantly higher than that in group B and C at each time point of T_2~T4 (P0.05), but the SBP of parturient in group A was significantly higher than that in group B and group C at each time point (P0.05). There was no significant difference in pH, blood gas index of umbilical artery blood and Apgar score after birth in group A (P0.05), but Apgar score of pH, in group C was significantly lower than that in group B (P0.05). The adverse reaction rate of parturient in group A was 2.11 significantly lower than that in group B (9.47)% and group C (13.68)% (P0.05). Conclusion low dose methoxifen can effectively maintain hemodynamics of parturient after combined spinal-epidural anesthesia in cesarean section, and has no adverse effect on newborn.
【作者單位】： 重慶市奉節(jié)縣人民醫(yī)院麻醉科;
【分類號】：R614
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，
本文編號：2382888
本文鏈接：http://sikaile.net/yixuelunwen/mazuiyixuelunwen/2382888.html
[Abstract]:Objective to investigate the effect of low dose methoxifen on hemodynamics of parturient and newborn during cesarean section anesthesia. Methods from January 2014 to June 2016, 285 cases of parturient undergoing combined spinal-epidural anesthesia were divided into 3 groups. Group A received intravenous injection of methoxifen hydrochloride 1 mg / g immediately after anesthesia, and group B received 2 mg of methoxifen hydrochloride immediately after anesthesia. In group C, normal saline was injected intravenously for 2 mL. The baseline value (T _ 0), 1min (T _ 2), 1min (T _ 4) and 1min (T _ 4) before delivery of fetus were recorded in group C, respectively, and were recorded immediately after anaesthesia supine position (T _ 1), 1min (T _ 2) after anaesthesia supine and 5min (T _ s _ 3) after anaesthesia. The changes of systolic blood pressure (SBP),) heart rate (HR), blood gas index (PO_2), partial pressure of carbon dioxide (PCO_2) in umbilical artery of newborn and 1min Apgar score of birth were measured at different time points of 5min (T5) after delivery. The adverse reactions such as nausea and vomiting in parturient were observed. Results in group B and group C, HR increased significantly and then decreased (P0.05), but the HR in group A was significantly lower than that in group B and C at each time point after T _ 1 began to decrease. There was no significant fluctuation (P0.05). The SBP of parturient in group A was significantly higher than that in group B and C at each time point of T_2~T4 (P0.05), but the SBP of parturient in group A was significantly higher than that in group B and group C at each time point (P0.05). There was no significant difference in pH, blood gas index of umbilical artery blood and Apgar score after birth in group A (P0.05), but Apgar score of pH, in group C was significantly lower than that in group B (P0.05). The adverse reaction rate of parturient in group A was 2.11 significantly lower than that in group B (9.47)% and group C (13.68)% (P0.05). Conclusion low dose methoxifen can effectively maintain hemodynamics of parturient after combined spinal-epidural anesthesia in cesarean section, and has no adverse effect on newborn.
【作者單位】： 重慶市奉節(jié)縣人民醫(yī)院麻醉科;
【分類號】：R614
【相似文獻(xiàn)】
相關(guān)期刊論文 前10條
1 徐健清;;甲氧明預(yù)防膝關(guān)節(jié)手術(shù)止血帶松氣后并發(fā)低血壓的效果[J];中國藥師;2012年09期
2 單立新;;肌肉注射甲氧明對下肢手術(shù)松止血帶后血流動(dòng)力學(xué)的影響[J];中國臨床藥理學(xué)與治療學(xué);2013年02期
3 任柏林;;靜脈預(yù)注小劑量甲氧明預(yù)防老年患者全身麻醉誘導(dǎo)期低血壓的療效觀察[J];中國醫(yī)藥導(dǎo)刊;2014年01期
4 司輝鋒;孟凡民;張加強(qiáng);李璐;;甲氧明對腹腔持續(xù)熱灌注老年患者血流動(dòng)力學(xué)的影響[J];中國老年學(xué)雜志;2014年09期
5 李璐;孫培春;孟凡民;張加強(qiáng);張輝;;甲氧明治療腰麻下剖宮產(chǎn)產(chǎn)婦術(shù)中低血壓的量-效關(guān)系[J];臨床麻醉學(xué)雜志;2014年05期
6 原保亭;;靜脈預(yù)注小劑量甲氧明預(yù)防老年患者全身麻醉誘導(dǎo)期低血壓的影響分析[J];醫(yī)學(xué)理論與實(shí)踐;2014年15期
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10 羅剛健;池信錦;關(guān)健強(qiáng);黎尚榮;黑子清;陳秉學(xué);;預(yù)注甲氧明對剖宮產(chǎn)患者腰硬聯(lián)合麻醉術(shù)中低血壓的防治作用[J];廣東醫(yī)學(xué);2007年09期
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2 王翔;不同劑量甲氧明與麻黃堿聯(lián)合預(yù)注對剖宮產(chǎn)母嬰的影響[D];山西醫(yī)科大學(xué);2015年
3 劉沖;預(yù)注不同劑量甲氧明在防治老年人股骨頭置換術(shù)中低血壓的臨床研究[D];長春中醫(yī)藥大學(xué);2015年
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5 司輝鋒;預(yù)輸注甲氧明對腹腔持續(xù)熱灌注老年患者血流動(dòng)力學(xué)及血?dú)獾挠绊慬D];鄭州大學(xué);2014年
6 劉偉;Coload并用麻黃堿、甲氧明和體位干預(yù)對腰硬聯(lián)合麻醉下剖宮產(chǎn)母嬰的影響[D];山東大學(xué);2012年
，本文編號：2382888
本文鏈接：http://sikaile.net/yixuelunwen/mazuiyixuelunwen/2382888.html
