【摘要】：目的觀察小劑量右美托咪定對婦科腹腔鏡手術(shù)患者眼內(nèi)壓(IOP)的影響。方法擇期全麻下行婦科腹腔鏡手術(shù)患者60例,年齡18~64歲,ASAⅠ或Ⅱ級,BMI 18~22kg/m2,隨機分為兩組:右美托咪定組(D組)和對照組(C組),每組30例。D組患者麻醉誘導(dǎo)前10min內(nèi)靜脈輸注右美托咪定0.4μg/kg,C組給予等容量生理鹽水。記錄麻醉前(基礎(chǔ)值,T0)、麻醉誘導(dǎo)后5 min(T1)、氣腹5min(T2)、體位改變后5min(T3)、體位改變后30min(T4)、氣腹60min(T5)和氣腹結(jié)束后10min(T6)時IOP和CVP;計算眼灌注壓,記錄術(shù)中高眼壓(眼內(nèi)壓21 mm Hg)的發(fā)生情況。結(jié)果與T0時比較,T1時兩組IOP、眼灌注壓及CVP明顯降低,T2~T5時C組IOP和CVP明顯升高、眼灌注壓明顯降低(P0.05)。與C組比較,T2~T5時D組IOP明顯降低,眼灌注壓明顯升高,T3~T5時D組CVP和高眼壓的發(fā)生率明顯降低(P0.05)。結(jié)論靜脈輸注右美托咪定0.4μg/kg可有效減輕婦科手術(shù)患者氣腹及體位因素導(dǎo)致的IOP升高。
[Abstract]:Objective to observe the effect of low dose dexmetomidine on intraocular pressure (IOP) in patients undergoing gynecological laparoscopic surgery. Methods Sixty patients with gynecologic laparoscopic surgery under general anesthesia, aged 18 to 64 years, with ASA grade 鈪，

本文編號：2324796