【摘要】：目的:觀察舒芬太尼聯(lián)合丙泊酚靜脈麻醉在經(jīng)陰道超聲取卵術(shù)中的安全性及臨床效果。方法:選取實(shí)施體外受精-胚胎移植術(shù)擬行經(jīng)陰道超聲無(wú)痛取卵術(shù)的育齡期婦女100例,隨機(jī)分為舒芬太尼復(fù)合丙泊酚組(S組)和芬太尼復(fù)合丙泊酚組(F組)。入室監(jiān)護(hù)生命體征后,S組靜脈注射舒芬太尼5μg,F組靜脈注射芬太尼50μg,消毒鋪巾后,兩組患者均緩慢靜脈注射丙泊酚70~75 mg。術(shù)中保持患者呼吸道通暢,有體動(dòng)或睜眼反應(yīng)時(shí)追加丙泊酚10~20mg。觀察并記錄兩組患者術(shù)前(靜脈注射丙泊酚前)、術(shù)中(手術(shù)開始后3 min)的平均動(dòng)脈壓(MAP)、心率(HR)、脈搏血氧飽和度(Sp O2);記錄手術(shù)時(shí)間、麻醉蘇醒時(shí)間(靜脈注射丙泊酚至意識(shí)恢復(fù)時(shí)間)、術(shù)中呼吸抑制、身體扭動(dòng)、術(shù)后惡心、嘔吐、眩暈的發(fā)生情況。結(jié)果:兩組患者一般資料、手術(shù)時(shí)間、麻醉蘇醒時(shí)間比較,差異無(wú)統(tǒng)計(jì)學(xué)意義;兩組患者的丙泊酚用量比較,S組明顯減少,差異有統(tǒng)計(jì)學(xué)意義(P0.05);與術(shù)前相比,兩組患者術(shù)中的MAP和HR明顯降低,但均在正常生理范圍內(nèi),Sp O2無(wú)顯著變化;兩組患者術(shù)中呼吸抑制、術(shù)后惡心、嘔吐、眩暈等發(fā)生情況比較,差異無(wú)統(tǒng)計(jì)學(xué)意義。S組患者體動(dòng)比F組顯著減少(P0.05)。結(jié)論:舒芬太尼復(fù)合丙泊酚能有效減少經(jīng)陰道超聲取卵術(shù)中患者體動(dòng)次數(shù),減少丙泊酚的用量,安全有效,麻醉效果好。
[Abstract]:Objective: to observe the safety and clinical effect of sufentanil combined with propofol intravenous anesthesia in transvaginal ultrasound. Methods: 100 women of childbearing age undergoing in vitro fertilization and embryo transfer were randomly divided into sufentanil combined propofol group (S group) and fentanyl combined propofol group (F group). After vital signs were monitored, sufentanil was injected intravenously into group S (5 渭 g) and fentanyl (50 渭 g) was injected intravenously in group F. After disinfecting and spreading towel, propofol 705mg was injected slowly into both groups. During operation, the respiratory tract was patency and propofol was added to 20 mg / g of propofol when there was body movement or eye opening reaction. The mean arterial pressure (map), heart rate (HR), pulse oxygen saturation (SPO _ 2) were observed and recorded before operation (before intravenous injection of propofol), during operation (3 min after operation), and the time of operation was recorded, and the mean arterial pressure (map), heart rate (HR) and pulse oxygen saturation (SPO _ 2) were recorded. Anaesthesia recovery time (intravenous injection of propofol to consciousness recovery time), intraoperative respiratory inhibition, body torsion, postoperative nausea, vomiting, vertigo occurrence. Results: there was no significant difference in general data, operation time and anaesthesia recovery time between the two groups. The dosage of propofol in the two groups was significantly reduced compared with that in group S (P0.05); compared with pre-operation, the dosage of propofol in two groups was significantly lower than that in group S (P0.05). Map and HR decreased significantly in both groups, but there was no significant change in SPO _ 2 in normal physiological range, the incidence of respiratory depression, postoperative nausea, vomiting and vertigo were compared between the two groups. There was no significant difference between group S and group F (P0.05). Conclusion: sufentanil combined with propofol can effectively reduce the number of body movements and the dosage of propofol during transvaginal ultrasound oocyte extraction.
【作者單位】： 山西省兒童醫(yī)院山西省婦幼保健院;
【分類號(hào)】：R614

【相似文獻(xiàn)】

相關(guān)期刊論文 前4條

1 馮紅斌;白虹;文依;李冬雪;李子嘉;陳麗紅;靳三慶;;不同滴定終點(diǎn)在無(wú)痛取卵術(shù)滴定麻醉中的比較[J];中山大學(xué)學(xué)報(bào)(醫(yī)學(xué)科學(xué)版);2014年01期

2 崔中璐;柴小青;方才;陳昆洲;;異丙酚復(fù)合芬太尼麻醉用于經(jīng)陰道取卵術(shù)臨床研究[J];安徽醫(yī)學(xué);2007年04期

3 馬袁英;沈艷;魯惠順;;不同劑量芬太尼在清醒麻醉陰道取卵術(shù)中的效果比較[J];浙江預(yù)防醫(yī)學(xué);2008年07期

4 ;[J];;年期

，

本文編號(hào)：2135007