【摘要】：目的:通過(guò)觀察幕上腫瘤切除術(shù)患者腫瘤壞死因子-α(TNF-α)、白細(xì)胞介素(IL)-8、IL-10、Ig M、Ig A及Ig G的水平來(lái)探討電針(EA)及經(jīng)皮穴位電刺激(TEAS)對(duì)免疫功能的影響是否相同。方法:120例患者被隨機(jī)分成3組:電針組(A組)、經(jīng)皮穴位電刺激組(B組)、單純?nèi)榻M(C組)。于麻醉前(T0)、誘導(dǎo)后4h(T1)、術(shù)后1d(T2)及術(shù)后2d(T3)采集外周血來(lái)檢測(cè)TNF-α、IL-8、IL-10、Ig M、Ig A及Ig G的水平。結(jié)果:與T0時(shí)間點(diǎn)相比,A組和B組的IL-10水平于T2、T3時(shí)間點(diǎn)明顯升高(P0.05);A組的IL-8水平于T2、T3時(shí)間點(diǎn)明顯升高(P0.05);C組的Ig A水平于T1、T2、T3時(shí)間點(diǎn)明顯降低(P0.05)。與A組相比,B組和C組的IL-8水平于T2、T3時(shí)間點(diǎn)明顯降低(P0.05),Ig A水平于T1、T2時(shí)間點(diǎn)降低程度明顯(P0.05)。結(jié)論:EA可以減輕幕上腫瘤切除術(shù)患者免疫功能的抑制。TEAS不能減輕幕上腫瘤切除術(shù)患者免疫功能的抑制。
[Abstract]:Objective: to observe the levels of tumor necrosis factor- 偽 (TNF- 偽), interleukin-8 (IL-10) IL-10 Ig A and IgA and IgG in supratentorial tumor resection patients to investigate whether the effects of electroacupuncture (EA) and transcutaneous acupoint electrical stimulation (TEAS) on immune function are the same. Methods 120 patients were randomly divided into three groups: electroacupuncture group (group A), percutaneous acupoint electrical stimulation group (group B) and general anesthesia group (group C). Before anesthesia (T0), 4 hours after induction (T1), 1 day after induction (T2) and 2 days after operation (T3), peripheral blood samples were collected to detect the levels of TNF- 偽 IL-8, IL-10, Ig, IgA and IgG. Results: the level of IL-10 in group A and group B was significantly higher than that in group T0 (P0.05). The level of IL-8 in group A was significantly higher than that in group T2T 3 (P0.05). The level of IgA in group C was significantly lower than that in group T1 (P0.05). Compared with group A, the level of IL-8 in group B and group C was significantly lower than that in group A (P0.05). Conclusion the inhibition of immune function in supratentorial tumor resection patients can be alleviated by 1: EA. Tea can not alleviate the inhibition of immune function in supratentorial tumor patients.
【作者單位】： 首都醫(yī)科大學(xué)電力教學(xué)醫(yī)院;首都醫(yī)科大學(xué)附屬北京天壇醫(yī)院;首都醫(yī)科大學(xué)附屬北京三博腦科醫(yī)院;
【基金】：國(guó)家重點(diǎn)基礎(chǔ)研究發(fā)展計(jì)劃(973計(jì)劃)項(xiàng)目(No.2013CB531901) 國(guó)家電網(wǎng)科學(xué)技術(shù)項(xiàng)目(No.SGHBOOOAJJS1400182)~~
【分類號(hào)】：R614;R739.4

【參考文獻(xiàn)】

相關(guān)期刊論文 前2條

1 韓潤(rùn)霞;楊晶;張?zhí)焐?張衛(wèi)東;;火針對(duì)類風(fēng)濕性關(guān)節(jié)炎大鼠血清白介素-1和腫瘤壞死因子-α的影響[J];針刺研究;2012年02期

2 劉U，

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