本文選題：麻醉藥物 + 配伍方式�。� 參考：《中國實用醫(yī)藥》2016年22期

【摘要】：目的探討不同麻醉藥物配伍對老年腹腔鏡手術術后認知的影響。方法 52例行腹腔鏡手術治療的老年患者,根據麻醉方式的不同將其分為A組(32例)和B組(20例)。B組采用七氟醚、瑞芬太尼聯合右美托咪定麻醉藥物配伍,A組采用異氟醚、芬太尼聯合咪唑安定等藥物配伍,比較兩組術后麻醉蘇醒狀況及簡易精神狀態(tài)量表(MMSE)評分。結果兩組定向力恢復時間比較差異具有統(tǒng)計學意義(P0.05)。術后2、12、24 h A組患者MMSE評分分別為(24.1±1.9)、(26.9±2.2)、(27.8±1.9)分,均明顯高于B組的(20.3±1.2)、(22.1±1.4)、(25.3±1.0)分(P0.05)。結論七氟醚、瑞芬太尼聯合右美托咪定等藥物配伍麻醉方式對老年腹腔鏡手術患者術后認知功能恢復期情況明顯優(yōu)于異氟醚、芬太尼聯合咪唑安定等藥物配伍,可在臨床推廣。
[Abstract]:Objective to investigate the effect of different anesthetic combinations on the postoperative cognition of elderly patients undergoing laparoscopic surgery. Methods 52 elderly patients undergoing laparoscopic surgery were divided into group A (n = 32), group B (n = 20) and group B (n = 20) treated with sevoflurane. Remifentanil combined with dexmetomidine was used in group A, and isoflurane was used in group A. Fentanyl combined with midazolam and other drugs were used to compare the recovery of anesthesia and the MMSE score. Results there was significant difference in the recovery time of directional force between the two groups (P 0.05). The MMSE scores in group A were 24.1 鹵1.9 and 26.9 鹵2.2 respectively, which were significantly higher than those in group B (20.3 鹵1.2) and 25.3 鹵1.0 (P 0.05) respectively. Conclusion the combination of sevoflurane, remifentanil and dexmetomidine is superior to isoflurane in the recovery of cognitive function in elderly patients undergoing laparoscopic surgery. Fentanyl combined with midazolam can be popularized in clinic.
【作者單位】： 河南省許昌市中心醫(yī)院南區(qū)醫(yī)院麻醉科;
【分類號】：R614

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