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碳酸利多卡因表面麻醉在纖維支氣管鏡檢查中的應用探討

發(fā)布時間:2018-06-06 08:52

  本文選題:碳酸利多卡因 + 鹽酸利多卡因; 參考:《廣西醫(yī)科大學》2014年碩士論文


【摘要】:目的:探討碳酸利多卡因(LC)在纖維支氣管鏡(FB)檢查中的應用價值。方法:選取在我院行FB檢查患者126例,隨機分為觀察組66例和對照組60例,在FB檢查過程中分別使用1.73%LC和2%鹽酸利多卡因(LH)行表面麻醉,每例患者使用藥物總劑量均為14m1。使用多參數監(jiān)護儀在FB檢查過程中監(jiān)測患者指脈氧(SPO2)、心率(HR)及呼吸頻率(RR)的變化情況,并計算指脈氧變異率(SPO2-VR)、心率變異率(HR-VR)及呼吸頻率變異率(RR-VR),記錄檢查時間及評價麻醉效果,并比較兩組間各參數的差異性。結果:1、觀察組及對照組的SP02-VR分別為4.17±4.54、5.62±5.37(P=0.1030.05),差異無統(tǒng)計學意義。2、觀察組及對照組的HR-VR分別為2.54±1.36、2.91±1.5(P=0.147>0.05),差異無統(tǒng)計學意義。3、觀察組及對照組的RR-VR分別為4.09±1.79、4.98±1.97(P=0.0090.05),差異有統(tǒng)計學意義。4、觀察組及對照組的FB檢查時間分別為8.59±3.73、8.55±3.27(P=0.9480.05),差異無統(tǒng)計學意義。5、觀察組的麻醉效果優(yōu)于對照組(P0.05),差異有統(tǒng)計學意義。結論:研究表明在FB檢查過程中,LC的麻醉效能優(yōu)于LH,使用LC的患者呼吸較平穩(wěn),建議在FB檢查中使用LC進行表面麻醉。
[Abstract]:Objective: to evaluate the value of lidocaine carbonate (LC) in fiberoptic bronchoscopy (FB). Methods: 126 patients with FB in our hospital were randomly divided into observation group (n = 66) and control group (n = 60). 1.73%LC and lidocaine hydrochloride (2% lidocaine hydrochloride) were used in the course of FB examination respectively. The total dose of each patient was 14ml. Multiparameter monitor was used to monitor the changes of SPO _ 2 (HRR) and respiratory frequency (RR) during FB examination, and to calculate the variability rate of phalanx (SPO _ 2-VRN), HR-VRR (HR-VRR) and RR-VRN, and to record the time of examination and evaluate the anesthetic effect. The differences of parameters between the two groups were compared. Results the SP02-VR of the observation group and the control group were 4.17 鹵4.54 鹵4.54 鹵5.62 鹵5.37, respectively, with no significant difference. The HR-VR of the observation group and the control group were 2.54 鹵1.36 鹵2.91 鹵1.5(P=0.147 > 0.05, respectively. The RR-VR of the observation group and the control group were 4.09 鹵1.794.98 鹵1.97 P0. 05, respectively. The difference was statistically significant. The time of FB in the observation group and the control group was 8.59 鹵3.73 鹵8.55 鹵3.27 P0. 948. 05, respectively. There was no significant difference between the observation group and the control group. The anesthetic effect of the observation group was better than that of the control group (P 0. 05), and the difference was statistically significant. Conclusion: the anaesthesia efficacy of LC in FB examination is better than that in LH.The patients who use LC have stable breathing. It is suggested that LC should be used for superficial anesthesia in FB examination.
【學位授予單位】:廣西醫(yī)科大學
【學位級別】:碩士
【學位授予年份】:2014
【分類號】:R614

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