發(fā)布時(shí)間：2018-05-21 08:30

  本文選題：七氟醚 + 年齡��； 參考：《中南大學(xué)》2014年碩士論文

【摘要】：目的：探討在相同七氟醚肺泡內(nèi)有效濃度下,不同年齡組和不同性別患者的腦電雙頻譜指數(shù)(Bispectral index, BIS)的變化；同時(shí)觀察在七氟醚麻醉誘導(dǎo)下,不同年齡組和不同性別患者的心率及平均動脈壓的變化。 方法：60例患者按年齡分成兩大組,分別為年輕組(20-40y)老年組(60y)；同時(shí)將上述兩大組患者按性別不同分為四組,分別為年輕男性組(Male young組)和年輕女性組(Female young組)；老年男性組(Male Old組)和老年女性組(Female Old組)。每組患者入室前均不使用術(shù)前用藥,入手術(shù)室后常規(guī)建立靜脈通道,除進(jìn)行常規(guī)心電監(jiān)測外,同時(shí)監(jiān)測直接動脈壓,BIS值以及吸入麻醉氣體監(jiān)護(hù),記錄其BIS,心率及平均動脈壓的基礎(chǔ)值；麻醉誘導(dǎo)使用8%七氟醚,氧流量為6L/min,當(dāng)BIS值為50以下并維持1min后,根據(jù)患者的體重置入相應(yīng)型號的喉罩,喉罩置入后將七氟醚濃度調(diào)整為2%,患者保持自主呼吸,并維持呼氣末二氧化碳濃度為35-45mmHg,當(dāng)氣體監(jiān)護(hù)儀顯示肺泡內(nèi)七氟醚濃度為2%時(shí),并維持10min。記錄第11min時(shí)候患者的BIS值,心率及平均動脈壓,觀察各組患者BIS值,以及血流動力學(xué)變化。 結(jié)果：年輕組(Y組)的BIS下降幅度低于老年組(0組)的BIS下降幅度,P0.05。年輕組和老年組中,不同性別之間的BIS下降幅度差異沒有統(tǒng)計(jì)學(xué)意義,P0.05。年輕組(Y組)的心率(heart rate, HR)變化值跟老年組(0組)的心率(HR)變化值的差異無統(tǒng)計(jì)學(xué)意義,P0.05。年輕組(Y組)的平均動脈壓下降值低于老年組(0組)的平均動脈壓(MAP)下降值,P0.05。在年輕組和老年組中,不同性別之間的心率(HR),平均動脈壓(MAP)的變化程度差異沒有統(tǒng)計(jì)學(xué)意義,P0.05。 結(jié)論：1、在相同濃度的七氟醚作用下,老年組的患者BIS下降的值要大于年輕組患者BIS下降的值； 2、在相同濃度的七氟醚作用下,老年組患者的心率變化值跟年輕組患者的心率變化值相似； 3、在相同濃度的七氟醚作用下,老年組患者的平均動脈壓(MAP)下降值要大于年輕組患者的MAP下降值； 4、在相同濃度的七氟醚作用下,相同年齡組的患者,不同性別之間的BIS,心率及平均動脈壓的變化程度沒有明顯差異。
[Abstract]:Objective: to investigate the changes of bispectral index (BISs) in patients with different age groups and different genders under the same effective concentration of sevoflurane, and to observe the changes of bispectral index (BISs) induced by sevoflurane anesthesia. Changes of heart rate and mean arterial pressure in different age groups and different genders. Methods Sixty patients were divided into two groups according to their age: the young group (20-40 yr), the elderly group (60 yg), and the two groups were divided into four groups according to their sex. Young male group (Male young group), young female group (Female young group), aged male group (Male Old group) and elderly female group (Female Old group). Each group of patients did not use preoperative medication before entering the room. After entering the operating room, venous channels were established routinely. In addition to routine ECG monitoring, BIS values of direct arterial pressure and monitoring of inhaled anesthetic gases were monitored at the same time. The basal values of BIS, heart rate and mean arterial pressure were recorded, 8% sevoflurane was used to induce anesthesia, the oxygen flow rate was 6 L / min, and when the BIS value was below 50 and 1min was maintained, the laryngeal mask was placed according to the patient's weight. After laryngeal mask placement, the concentration of sevoflurane was adjusted to 2. The patient maintained spontaneous respiration and maintained end-expiratory carbon dioxide concentration of 35-45 mm Hg.When the gas monitor showed that the concentration of sevoflurane in the alveoli was 2 and maintained for 10 minutes. The BIS, heart rate and mean arterial pressure were recorded at the time of 11min. The BIS values and hemodynamic changes were observed. Results: the decrease of BIS in the young group was lower than that in the old group (P 0.05). There was no significant difference in the decrease of BIS between the young group and the elderly group (P 0.05). There was no significant difference in heart rate and heart rate between the young group and the old group (P 0.05). The decrease value of mean arterial pressure in young group (P < 0.05) was lower than that in group (0) (P < 0.05). There was no significant difference in the changes of heart rate HRV and mean arterial pressure (MAPP) between young group and elderly group (P 0.05). Conclusion under the same concentration of sevoflurane, the decrease of BIS in the elderly group was higher than that in the young group. 2. Under the same concentration of sevoflurane, the change of heart rate in the elderly group was similar to that in the young group. 3. Under the same concentration of sevoflurane, the decrease of mean arterial pressure (MAP) in the elderly group was higher than that in the young group. 4. Under the same concentration of sevoflurane, there was no significant difference in BIS, heart rate and mean arterial pressure between different genders in the same age group.
【學(xué)位授予單位】：中南大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R614

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 龔琬玲;黃時(shí)俊;司歌;張凱燕;陳仲本;;多模式音頻脈沖信號光電穴位刺激對高血壓大鼠血液流變性及血壓的影響[J];生物醫(yī)學(xué)工程學(xué)雜志;2012年03期

，

本文編號：1918476