本文選題：右美托咪定 + 懸雍垂腭咽成形術　； 參考：《中國醫(yī)藥科學》2016年19期

【摘要】：目的觀察懸雍垂腭咽成形術(UPPP)中右美托咪定對術后鎮(zhèn)靜效果。方法 2014年10月~2015年12月筆者所在醫(yī)院阻塞性睡眠呼吸暫停綜合征(OSAS)全麻下行UPPP的患者60例,將患者隨機方式分為對照組(S組)和右美托咪定組(D組),每組30例。D組靜脈輸注右美托咪定在手術結束前30min,0.5μg/kg為注射劑量,持續(xù)注射15min,S組輸注生理鹽水。記錄各組血液動力學變化及術后躁動及疼痛程度。結果 D組拔管時、拔管后心率和平均動脈低于S組;D組中蘇醒期躁動發(fā)生率顯著低于S組;D組拔管后5min和術后24h VAS評分低于S組,嗎啡使用人數(shù)也少于S組,差異均有統(tǒng)計學意義(P0.05)。結論應用右美托咪定在UPPP手術中可以維護患者麻醉蘇醒期間血流動力學趨穩(wěn)定,并明顯減少蘇醒期的躁動且鎮(zhèn)痛效果良好。
[Abstract]:Objective to observe the sedation effect of right metoimidine in uvulopalatopharyngoplasty (UPPP) after operation. Methods from October 2014 to December 2015, 60 patients with obstructive sleep apnea syndrome (OSAS) were treated with UPPP under general anesthesia. The patients were randomly divided into control group (S group) and dexmetomidine group (group D). 30 patients in group D were given dexmetomidine 30 minutes before the end of operation. The dosage of dexmetomidine was 0.5 渭 g/kg before the end of operation, and normal saline was continuously injected into group S for 15 minutes. Hemodynamic changes and postoperative restlessness and pain were recorded. Results during extubation, the heart rate and mean arterial restlessness in group D were significantly lower than those in group S (P < 0.05). The 5min and VAS scores in group D were significantly lower than those in group S and the number of morphine users was also lower than that in group S. The difference was statistically significant (P 0.05). Conclusion the use of dexmetidine in UPPP surgery can maintain hemodynamic stability during anaesthesia recovery, reduce restlessness during anaesthesia, and have a good analgesic effect.
【作者單位】： 廣東省佛山禪城華南耳鼻咽喉專科醫(yī)院麻醉科;
【分類號】：R614

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