本文選題：下腹部手術(shù)　切入點：長期飲酒　出處：《海南醫(yī)學院學報》2016年21期

【摘要】：目的:發(fā)現(xiàn)長期飲酒對下腹部手術(shù)患者術(shù)中麻醉抗藥及術(shù)后認知功能的影響。方法:118例接受下腹部手術(shù)的患者納入研究,分為長期飲酒組43例,對照組75例。對比兩組患者的圍麻醉期血流動力學指標、應激指標,術(shù)后血清氨基酸遞質(zhì)、神經(jīng)功能指標含量差異。結(jié)果:長期飲酒組患者的劃皮時(T2)、切口縫合時(T3)血流動力學指標CO、VO2值大于對照組患者,SV值小于對照組患者,應激指標Glu、Cor、AngⅡ、E、NE含量高于對照組患者;長期飲酒組患者的術(shù)后血清Glu、Asp、Gly、GABA、Ala、Tau含量高于對照組患者,NSE、S100β、MMP-9含量高于對照組患者,BDNF、ADP含量低于對照組患者。結(jié)論:長期飲酒可增加下腹部手術(shù)患者的麻醉抗藥性,增加術(shù)后認知功能障礙發(fā)生率。
[Abstract]:Objective: to explore the effect of long-term drinking on anesthesia resistance and postoperative cognitive function in patients undergoing lower abdominal surgery.Methods one hundred and eighty-eight patients undergoing lower abdominal surgery were divided into two groups: chronic drinking group (n = 43) and control group (n = 75).The hemodynamic index, stress index, serum amino acid transmitter and nerve function index were compared between the two groups.Results: in the patients with chronic drinking, the blood flow index COV _ 2 was higher than that in the control group, and the stress index was higher than that in the control group, and the content of Glu-Corn Ang 鈪，

本文編號：1698360