發(fā)布時(shí)間：2018-03-21 11:24

  本文選題：右旋美托咪定　切入點(diǎn)：全身麻醉　出處：《醫(yī)學(xué)理論與實(shí)踐》2017年24期 　論文類型：期刊論文

【摘要】：目的:對(duì)胸腰椎骨折的患者給予右旋美托咪定全身麻醉,分析圍拔管期血流動(dòng)力學(xué)的情況。方法:將我院接受治療的74例胸腰椎骨折的患者平均分為兩組進(jìn)行麻醉,研究組患者在10min內(nèi)靜脈泵注負(fù)荷量1μg/kg的右旋美托咪定進(jìn)行全麻,同時(shí)給予0.2~0.6μg/kg(kg·h)的速度進(jìn)行維持,對(duì)照組給予常規(guī)誘導(dǎo)麻醉,術(shù)后拔管后停右旋美托咪定,對(duì)右旋美托咪定麻醉誘導(dǎo)、氣管插管、拔管時(shí)的血流動(dòng)力學(xué)情況和心腦血管并發(fā)癥的情況進(jìn)行分析。結(jié)果:兩組患者在插管和拔管時(shí)的MAP、SpO2、HR均有明顯的升高,且對(duì)照組的升高程度明顯高于研究組,差異有統(tǒng)計(jì)學(xué)意義(P0.05),患者術(shù)后并發(fā)癥的發(fā)生率組間數(shù)據(jù)對(duì)比差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:采用右旋美托咪定進(jìn)行全麻在圍拔管時(shí)期具有較好的效果,可以有效控制患者的血流動(dòng)力學(xué)變化,減少對(duì)患者心臟和血壓的影響,有效減少拔管期的應(yīng)激反應(yīng),維持血流動(dòng)力學(xué)穩(wěn)定,值得臨床推廣。
[Abstract]:Objective: to analyze hemodynamics in patients with thoracolumbar fracture treated with dexmetomidine during extubation. Methods: 74 patients with thoracolumbar fractures received treatment in our hospital were divided into two groups. Patients in the study group received general anesthesia with intravenous infusion of 1 渭 g / kg dexmetomidine within 10 minutes, and were maintained at the speed of 0.2V 0.6 渭 g / kg / kg 路h. The control group was given routine induction anesthesia, and after extubation, dexmetoimidine was stopped after extubation. The hemodynamics and cardiovascular and cerebrovascular complications during anesthesia induction, tracheal intubation, extubation of dexmetidine were analyzed. Results: MAPMA-SpO2 HR was significantly increased in both groups during intubation and extubation. The degree of increase in the control group was significantly higher than that in the study group. The difference was statistically significant (P 0.05), and there was no significant difference in the incidence of postoperative complications among the groups. Conclusion: the general anesthesia with dexmetomidine has a good effect in the period of extubation. It can effectively control the hemodynamic changes of patients, reduce the influence on heart and blood pressure, reduce the stress response during extubation, and maintain the hemodynamic stability, which is worthy of clinical promotion.
【作者單位】： 湖北省洪湖市人民醫(yī)院麻醉科;
【分類號(hào)】：R614.2
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本文編號(hào)：1643640