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  本文選題：臨床觀察　切入點：下肢手術(shù)　出處：《北方藥學(xué)》2016年06期 　論文類型：期刊論文

【摘要】：目的:探析下肢手術(shù)進(jìn)行不同劑量右美托咪定麻醉對蘇醒期躁動的臨床效果觀察及安全性研究。方法:臨床選擇2014年6月~2015年6月本院收治的下肢手術(shù)病例100例,根據(jù)隨機(jī)數(shù)字表法分為對照組和觀察組,每組50例,觀察組予以0.5μg/kg右美托咪定聯(lián)合腰硬聯(lián)合麻醉,對照組予以0.25μg/kg右美托咪定聯(lián)合腰硬麻醉,記錄給藥前(T0)、給藥5min(T1)、給藥30min(T2)、給藥1h(T3)、結(jié)束手術(shù)時(T4)的呼吸頻率(RR)、平均動脈壓(MAP)、心率(HR)等指標(biāo);比較記錄給藥前(T0)、給藥5min(T1)、給藥30min(T2)、給藥1h(T3)、結(jié)束手術(shù)時(T4)的術(shù)中鎮(zhèn)靜效果。結(jié)果:觀察組給藥5min(T1)、給藥30min(T2)、給藥1h(T3)、結(jié)束手術(shù)時(T4)的RR、MAP、HR等指標(biāo)顯著優(yōu)于對照組,差異有統(tǒng)計學(xué)意義(P0.05);觀察組給藥5min(T1)、給藥30min(T2)、給藥1h(T3)、結(jié)束手術(shù)時(T4)的鎮(zhèn)靜效果顯著優(yōu)于對照組,差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論:下肢手術(shù)予以0.5μg/kg右美托咪定腰硬聯(lián)合麻醉術(shù)中患者生命體征平穩(wěn),鎮(zhèn)靜效果較佳,值得臨床推廣。
[Abstract]:Objective: to investigate the clinical effect and safety of dexmetomidine anesthesia in lower extremity operation in patients with restlessness during recovery period. Methods: from June 2014 to June 2015, 100 cases of lower extremity operation were selected. According to the random number table method, the control group and the observation group were divided into two groups, 50 cases in each group. The observation group was given 0.5 渭 g / kg dexmetidine combined with spinal-epidural anesthesia, and the control group was given 0.25 渭 g / kg dexmetidine combined with spinal-epidural anesthesia. The respiratory frequency, mean arterial pressure (MAPP), heart rate (HRR) of T0, T1, T2, T2, T3, T4 at the end of operation were recorded. Results: the intraoperative sedative effects of T0, T0, T1, T2, T3, T4 at the end of operation in the observation group were significantly better than those in the control group (5 min, 30 min, 30 min, 1 h, and 1 h, respectively), and the results showed that the RRMP-MAPHR of the observation group was significantly better than that of the control group (P < 0.05), and that of the observation group was significantly higher than that of the control group (P < 0.01). The results showed that the RRRMAPHR in the observation group was significantly better than that in the control group in 5 min, 30 min, 1 h, and 1 h, respectively. The sedation effect of the observation group was significantly better than that of the control group, and the sedation effect of the observation group was significantly better than that of the control group, and the sedative effect of the observation group was better than that of the control group, and the sedative effect of the observation group was better than that of the control group, and that of the observation group was better than that of the control group. The difference was statistically significant (P 0.05). Conclusion: the vital signs of patients undergoing lower extremity surgery with 0.5 渭 g / kg dexmetomidine were stable, and the sedation effect was better, which is worthy of clinical promotion.
【作者單位】： 甘肅省武威市涼州區(qū)醫(yī)院麻醉手術(shù)科;甘肅省武威市涼州區(qū)醫(yī)院重癥醫(yī)學(xué)科;
【分類號】：R614

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本文編號：1631309