本文關鍵詞： 布托啡諾 右美托咪定 頸叢阻滯麻醉 甲狀腺手術　出處：《中國藥物經(jīng)濟學》2016年08期 　論文類型：期刊論文

【摘要】：目的探討布托啡諾復合右美托咪定治療頸叢阻滯麻醉下甲狀腺手術患者的臨床效果。方法選取2014年6月至2015年6月沈陽市紅十字會醫(yī)院收治的甲狀腺手術患者64例為研究對象,按隨機數(shù)字表法分為研究組和對照組,每組32例。兩組患者均行頸叢阻滯麻醉,研究組患者在此基礎上應用布托啡諾復合右美托咪定,比較兩組患者不同時點平均動脈壓(MAP)、心率(HR)、警覺/鎮(zhèn)靜(OAA/S)評分變化、神經(jīng)阻滯時間及藥物安全性等。結果進入手術室時及神經(jīng)阻滯時兩組患者MAP、HR、OAA/S評分比較,差異均無統(tǒng)計學意義(均P0.05);切皮時、分離腫瘤時及手術結束時研究組患者MAP、HR、OAA/S評分與對照組比較,差異均有統(tǒng)計學意義(均P0.05)。研究組患者麻醉阻滯起效時間、阻滯持續(xù)時間及鎮(zhèn)痛持續(xù)時間均優(yōu)于對照組,差異均有統(tǒng)計學意義(均P0.05);兩組患者均無嚴重不良反應發(fā)生。結論布托啡諾復合右美托咪定用于頸叢阻滯麻醉下甲狀腺手術應用效果顯著,鎮(zhèn)痛效果小,血流動力學穩(wěn)定,不良反應發(fā)生率低。
[Abstract]:Objective to investigate the clinical effect of butorphanol combined with dexmetomidine in the treatment of thyroid surgery under cervical plexus block anesthesia. Sixty-four patients undergoing glandular surgery were studied. According to the random number table method, the patients in each group were divided into study group and control group, 32 cases in each group. All patients in both groups were treated with cervical plexus block anesthesia, and the patients in study group were treated with butorphanol combined with dexmetomidine on this basis. The mean arterial pressure (map), heart rate (HRN), alertness / sedation (OAA / S) scores at different time points were compared between the two groups. Results there was no significant difference in MAPHR-OAA / S score between the two groups when entering the operating room and during nerve block (all P 0.05). The OAA / S scores of patients in the study group were compared with those in the control group at the time of skin incision, separation of tumor and the end of operation. All the differences were statistically significant (P 0.05). The onset time of anesthesia block, the duration of block and the duration of analgesia in the study group were better than those in the control group, and the difference was statistically significant (all P 0.05). Conclusion butorphanol combined with dexmetomidine is effective in thyroid surgery under cervical plexus block anesthesia, with little analgesic effect and stable hemodynamics. The incidence of adverse reactions was low.
【作者單位】： 沈陽市紅十字會醫(yī)院;
【分類號】：R614
【正文快照】： 甲狀腺位于人體頸部,周圍神經(jīng)及血管豐富,甲狀腺手術中危險因素較多,采用傳統(tǒng)頸叢神經(jīng)阻滯麻醉術后容易出現(xiàn)聲音嘶啞、嗆咳、窒息等,不利于患者的術后恢復[1]。甲狀腺手術中麻醉方式對手術安全性有直接影響。近年來,頸叢神經(jīng)阻滯麻醉在甲狀腺手術患者中取得了良好的應用效果[2

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