【摘要】：目的 腎病綜合征出血熱是由幾種嚙齒動物攜帶的多種不同型漢坦病毒引起的伴有腎綜合征的一類出血熱的綜合名稱,是在世界上分布較廣,發(fā)病較多,危害性較大的一種病毒性出血熱,已成為全球性的公共衛(wèi)生問題�，F(xiàn)對1997～2005年天津市東麗區(qū)腎病綜合征出血熱流行因素進行研究,以制定科學(xué)的預(yù)防措施,減少動物疫源性疾病向人間的傳播,避免新的傳染病的發(fā)生,保證社會秩序的順利發(fā)展。 方法 對東麗區(qū)1997～2005腎病綜合征出血熱流行狀況進行統(tǒng)計描述和相關(guān)分析,對鼠帶毒率、氣象資料、農(nóng)業(yè)資料、人口資料采用Excel進行資料整理,并將發(fā)病情況與流行因素采用SPSS11.5軟件包進行統(tǒng)計分析。 結(jié)果 天津市東麗區(qū)腎病綜合征出血熱自1997年開始出現(xiàn)流行趨勢,之后逐漸增多到2002年達到高峰,之后逐年下降。9年共發(fā)生腎病綜合征出血熱105例,死亡4例,累計發(fā)病率為2.90/10萬,死亡率為0.11/10萬,病死率3.81%;具有明顯的季節(jié)差異,4～5月為發(fā)病高峰,占發(fā)病總數(shù)的44.76%;呈高度散發(fā),全區(qū)11個鄉(xiāng)鎮(zhèn)街70個行政村都有病例發(fā)生;30歲組發(fā)病數(shù)最高,占總發(fā)病數(shù)的33.33%;男性多于女性,男女之比為3.57∶1;農(nóng)民發(fā)病人數(shù)占總發(fā)病人數(shù)的26.67%,外地流動人口發(fā)病占發(fā)病總數(shù)的54.29%;經(jīng)檢驗鼠帶毒指數(shù)與疫情發(fā)病率基本趨勢一致;平均氣溫與發(fā)病率呈正相關(guān)(r_s=0.746,P=0.021);降水量與發(fā)病率呈負(fù)相關(guān)(r_s=-0.695,P=0.038);糧食種植面積與發(fā)病率呈負(fù)相關(guān)趨勢(r_s=-0.167,P=0.532)。 結(jié)論 東麗區(qū)屬于原始宿主為褐家鼠的Ⅱ型漢城病毒引起的以家鼠型疫情為主的疫區(qū)。90年代中期以后流動人口的大量涌人;本地區(qū)優(yōu)勢鼠種的變遷;
[Abstract]:Objective hemorrhagic fever with nephrotic syndrome (HFRS) is a kind of hemorrhagic fever with renal syndrome caused by a variety of different types of Hantavirus carried by several rodents, and it is widely distributed in the world. A serious viral hemorrhagic fever has become a global public health problem. The epidemic factors of hemorrhagic fever with nephrotic syndrome (HFRS) in Dongli district of Tianjin in 1997 / 2005 were studied in order to formulate scientific preventive measures to reduce the spread of animal epidemic diseases to human and to avoid the occurrence of new infectious diseases. To ensure the smooth development of social order. Methods the epidemic situation of hemorrhagic fever with nephrotic syndrome (HFRS) in Dongli district in 1997-2005 was described statistically and analyzed. The rate of virus-carrying, meteorological data, agricultural data and population data in Dongli district were collected by Excel. The incidence and epidemic factors were analyzed by SPSS11.5 software package. Results the epidemic trend of hemorrhagic fever with nephrotic syndrome (HFRS) in Dongli district of Tianjin began in 1997, then increased gradually to the peak in 2002, and then decreased year by year. There were 105 cases of hemorrhagic fever with nephrotic syndrome (HFRS) and 4 cases of death in 9 years. The cumulative morbidity was 2.90 / one hundred thousand, the mortality was 0.11 / one hundred thousand and the mortality was 3.81%. There were obvious seasonal differences, the incidence peak was from April to May, accounting for 44.76% of the total number of cases, showing a high degree of distribution, 11 rural streets and 70 administrative villages in the whole region had cases occurring, the incidence of the 30-year-old group was the highest, accounting for 33.33% of the total number of cases, the number of cases in the 30-year-old group was the highest. Male was more than female, the ratio of male to female was 3.57%, the number of peasants was 26.67%, the floating population accounted for 54.29% of the total, the virus-carrying index of tested mice was consistent with the incidence rate of epidemic situation. There was a positive correlation between mean air temperature and incidence (r = 0.746, P = 0.021), and a negative correlation between precipitation and incidence (r = 0.695, P = 0.038). There was a negative correlation between grain planting area and incidence (r = 0.167, P = 0.532). Conclusion Dongli district belongs to the endemic area mainly caused by type 鈪，

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