【摘要】：二氧化氯(簡寫為ClO_2)被公認(rèn)為一種廣譜、高效、快速、低毒的消毒劑,已廣泛應(yīng)用于環(huán)境物體表面、食品加工設(shè)備、餐飲容器與水的消毒等各方面。近年來,重慶市申報ClO_2消毒劑的生產(chǎn)廠家逐年增加,劑型種類繁多,產(chǎn)品標(biāo)準(zhǔn)和質(zhì)量參差不齊。我們在實(shí)際工作中發(fā)現(xiàn),單純用國家檢測規(guī)范中的殺菌效果指標(biāo)進(jìn)行同類產(chǎn)品的鑒定不能完全體現(xiàn)ClO_2消毒劑的特點(diǎn),不能明確描述其質(zhì)量高低,不利于指導(dǎo)和監(jiān)督廠家提高產(chǎn)品質(zhì)量,給消毒劑使用單位推薦產(chǎn)品時也缺乏科學(xué)的依據(jù)。因此,在實(shí)驗(yàn)室對康保潔牌二氧化氯固體消毒劑(簡寫為康保潔ClO_2)進(jìn)行了殺菌效果的系統(tǒng)分析,觀察其特性和殺菌效果變化規(guī)律,從多方面評價該消毒劑的質(zhì)量,探討同類產(chǎn)品可能增加的有效評價指標(biāo)。也借此工作為ClO_2消毒劑質(zhì)量的系統(tǒng)評價奠定實(shí)驗(yàn)基礎(chǔ)。 為了解康保潔ClO_2的殺菌性能、穩(wěn)定性及其影響因素,我們在實(shí)驗(yàn)室對其進(jìn)行了不同活化條件下的ClO_2含量測定、懸液定量殺滅試驗(yàn)、殺菌影響因素測定、加速穩(wěn)定性試驗(yàn)、能量試驗(yàn),并通過現(xiàn)場與模擬現(xiàn)場消毒試驗(yàn)驗(yàn)證了該消毒劑的實(shí)用消毒效果。采用氣相色譜法測定其消毒副產(chǎn)物,驗(yàn)證ClO_2消毒的優(yōu)越性。研究結(jié)果如下: 1. 康保潔ClO2 為二元包裝,A 劑主要成分為亞氯酸鈉與穩(wěn)定劑碳酸鈉,呈白色粉末狀,其中亞氯酸鈉含量≥82%,B 劑為活化劑檸檬酸,為白色細(xì)小顆粒。使用時取等量A 劑、B 劑加入適量水活化一定時間,亞氯酸鹽在檸檬酸的激活下釋放出具有活性功能的游離ClO_2。ClO_2釋出濃度隨活化水量增多而降低,活化時間的延長而增高,活化至4h 后下降。經(jīng)殺菌試驗(yàn)驗(yàn)證, 1.0gA 劑與1.0gB 劑以5.0ml 水活化4h,此時能釋出ClO2 90.79mg/g,與不同活化條件的康保潔ClO_2相比較,其殺滅微生物作用最強(qiáng)。 2. 康保潔ClO_2 屬穩(wěn)定類消毒劑,具有高效、快速的殺菌特點(diǎn)。225mg/L 康保潔ClO2 對細(xì)菌芽胞作用2min 或150mg/L 作用15min,5mg/L 對銅綠假單胞菌作用1min,7.5mg/L 對金黃色葡萄球菌作用1min 或5mg/L 作用3min,7.5mg/L 對大腸桿菌作用3min,殺滅對數(shù)值均≥5.00,7.5mg/L 康保潔ClO_2 對白色念珠菌作用3min 或5mg/L作用7min,其殺滅對數(shù)值均≥4.00,達(dá)消毒合格要求。 3. 康保潔ClO_2 可用于多次消毒污穢物品,其實(shí)用參考劑量為10mg/L。5mg/L 康
[Abstract]:Chlorine dioxide (ClO_2) has been recognized as a broad-spectrum, efficient, rapid, low-toxic disinfectant, has been widely used in the surface of environmental objects, food processing equipment, catering containers and water disinfection and so on. In recent years, the manufacturers of ClO_2 disinfectant declared by Chongqing have increased year by year, the dosage forms are various, and the product standard and quality are not uniform. In our practical work, we found that the identification of the same kind of products with the germicidal efficacy index in the national standard can not fully reflect the characteristics of the ClO_2 disinfectant, and can not clearly describe the quality of the disinfectant. It is not conducive to guide and supervise manufacturers to improve the quality of products, and there is no scientific basis for recommending products to disinfectant users. Therefore, the germicidal efficacy of Kangbaojie brand chlorine dioxide solid disinfectant (ClO_2) was systematically analyzed in the laboratory, and its characteristics and bactericidal effect were observed, and the quality of the disinfectant was evaluated from many aspects. This paper discusses the effective evaluation index which may be increased by the same kind of products. This work also lays an experimental foundation for the systematic evaluation of the quality of ClO_2 disinfectant. In order to understand the germicidal performance, stability and influencing factors of Kangpaojie ClO_2, we measured the content of ClO_2 under different activation conditions, the suspension quantitative killing test and the influence factors of germicidal activity in the laboratory. Accelerated stability test, energy test, and field and simulated disinfection tests verified the practical disinfection effect of the disinfectant. Gas chromatography was used to determine its disinfection by-products to verify the advantages of ClO_2 disinfection. The results of the study are as follows: 1. Kangpaojie ClO2 is a binary package. The main composition of agent A is sodium chlorite and stabilizer sodium carbonate, in which the content of sodium chlorite is more than 82%, and agent B is citric acid, which is a fine white particle. The release concentration of free ClO_2.ClO_2 with active function decreased with the increase of activated water amount, and the release concentration of free chlorite with active function was decreased with the increase of activated water amount, and the release concentration of free chlorite with active function was decreased with the increase of activated water quantity. The activation time increased and decreased after 4 h activation. The germicidal test showed that 1.0gA and 1.0gB were activated with 5.0ml water for 4 h, and then ClO2 90.79 mg 路kg-1 was released. Compared with Kangpaojie ClO_2 with different activation conditions, its bactericidal effect was the strongest. 2. Kangpaojie ClO_2 is a stable disinfectant with high efficiency and rapid bactericidal properties. 225 mg/L Kangpaojie ClO2 treated bacterial spores with 2min or 150mg/L for 15 min and 5 mg / L against Pseudomonas aeruginosa for 1 min. When 7.5mg/L was exposed to 1min or 5mg/L for 3 min and 7.5 mg / L to Escherichia coli for 3 min, the killing logarithm was 鈮，

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