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諾如病毒GⅡ.17新變異株引致福建省2014~2015年病毒性胃腸炎暴發(fā)

發(fā)布時(shí)間:2018-11-07 11:19
【摘要】:本文旨在鑒定福建省2014~2015年冬季導(dǎo)致病毒性胃腸炎暴發(fā)的病原體,并對(duì)病原體進(jìn)行分子特征研究。收集福建省2014~2015年胃腸炎暴發(fā)期間急性病例的標(biāo)本,開(kāi)展諾如病毒檢測(cè)并對(duì)衣殼蛋白基因片段進(jìn)行分子特征分析。共檢測(cè)3起暴發(fā)疫情標(biāo)本31份,檢出GⅡ型諾如病毒陽(yáng)性標(biāo)本17份。測(cè)序結(jié)果證實(shí)有13份標(biāo)本為諾如病毒GⅡ.17新變異株,與2014年日本毒株Kawasaki 323同源性最高,在系統(tǒng)進(jìn)化上形成一個(gè)新的獨(dú)立的分枝,有別于近年來(lái)本地散發(fā)流行及全球暴發(fā)流行的優(yōu)勢(shì)基因型GⅡ.4。是福建省內(nèi)首次檢出諾如病毒GⅡ.17,并引起病毒性胃腸炎暴發(fā)。
[Abstract]:The purpose of this paper is to identify the pathogen that caused the outbreak of viral gastroenteritis in Fujian Province in the winter of 2014-2015, and to study the molecular characteristics of the pathogen. The samples of acute cases of gastroenteritis during 2014-2015 in Fujian Province were collected, and the norovirus detection was carried out and the molecular characteristics of capsid protein gene fragments were analyzed. A total of 31 specimens of 3 outbreaks were detected and 17 positive specimens of G 鈪,

本文編號(hào):2316194

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