【摘要】：目的對貴陽市2009-2013年確診報(bào)告的4例人感染高致病性禽流感病例進(jìn)行流行病學(xué)分析,為進(jìn)一步科學(xué)防控人禽流感提供依據(jù)。方法對確診病例按衛(wèi)生部《人感染高致病性禽流感流行病學(xué)調(diào)查方案》進(jìn)行個(gè)案調(diào)查,采用RT-PCR或Real Time-PCR法對病例呼吸道標(biāo)本及外環(huán)境標(biāo)本進(jìn)行流感病毒核酸檢測。結(jié)果 4例病例首發(fā)癥狀均有發(fā)熱等流感樣癥狀,1例治愈,3例死亡。在發(fā)病后6 d發(fā)現(xiàn)并報(bào)告,在發(fā)病后8.5 d確診。4例病例發(fā)病前均無外出及病死禽接觸史。3例近距離接觸過活禽,1例接觸速凍生禽�？梢杀┞锻猸h(huán)境中檢測出H5陽性。結(jié)論加強(qiáng)不明原因肺炎病例監(jiān)測,及早發(fā)現(xiàn)人禽流感病例,早期開展有效的治療,可以降低人禽流感病例的病死率。被禽流感病毒污染的農(nóng)貿(mào)市場外環(huán)境及速凍生禽是可能的傳染源。
[Abstract]:Objective to analyze the epidemiology of 4 cases of highly pathogenic avian influenza (HPAI) reported from 2009 to 2013 in Guiyang, and to provide scientific basis for the prevention and control of human avian influenza. Methods cases of confirmed cases were investigated according to the Epidemiological investigation Program of highly pathogenic Avian Influenza infection in Human Health Ministry. Influenza virus nucleic acid was detected by RT-PCR or Real Time-PCR method in respiratory tract samples and external environment samples. Results all the first symptoms of 4 cases had flu-like symptoms such as fever, 1 case was cured and 3 cases died. On the 6th day after onset, we found and reported that the diagnosis was confirmed on the 8.5 day after the onset of the disease. 4 cases had no history of contact with sick and dead birds before onset. 3 cases were in close contact with live poultry, and 1 case was exposed to quick-frozen live poultry. H5 positive was detected in suspicious exposed environment. Conclusion strengthening surveillance of unknown pneumonia cases, early detection of human avian influenza cases and early effective treatment can reduce the mortality of human avian influenza cases. The environment of farmers' market polluted by avian influenza virus and frozen poultry are the possible source of infection.
【作者單位】： 貴陽市疾病預(yù)防控制中心流行病科;
【分類號(hào)】：R181.3;R511.7

【參考文獻(xiàn)】

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