本文選題：甲狀腺結(jié)節(jié) + 危險因素　； 參考：《衛(wèi)生研究》2017年06期

【摘要】：目的了解浙江省居民的甲狀腺結(jié)節(jié)患病現(xiàn)況,探討甲狀腺結(jié)節(jié)的相關(guān)危險因素。方法采用分層整群抽樣方法,于2010年3—12月抽取浙江省22個縣區(qū),對18 956名常住人口和生活3年以上外來人員進行問卷調(diào)查(包括一般情況、生活及飲食習(xí)慣、自身健康狀況及疾病史等),并進行甲狀腺B超和水碘、鹽碘、尿碘等檢測,計算不同地區(qū)不同人群甲狀腺結(jié)節(jié)患病率,描述甲狀腺結(jié)節(jié)相關(guān)因素的分布水平,并運用Logistic回歸分析可能影響甲狀腺結(jié)節(jié)的危險因素。結(jié)果浙江省居民甲狀腺結(jié)節(jié)患病率為21.78%(4129人),其中單發(fā)結(jié)節(jié)患病率為11.75%(2227人),高于多發(fā)結(jié)節(jié)的10.03%(1902人)(χ~2=281.44,P0.05);男性甲狀腺結(jié)節(jié)患病率為16.60%(1324人),低于女性的25.59%(2795人)(χ~2=218.60,P0.05),城市居民為23.62%(2226人),高于農(nóng)村居民的19.97%(1903人)(χ~2=922.53,P0.05),且均隨年齡增長而逐漸升高(χ~2=36.99,P0.05);沿海、次沿海和內(nèi)陸地區(qū)甲狀腺結(jié)節(jié)患病率依次為25.05%(1927人)、20.27%(1343人)和18.52%(859人)(χ~2=85.84,P0.05);文化程度高、常吃海產(chǎn)品、生氣頻率高、有甲狀腺疾病患病史[OR(95%CI)分別為1.11(1.06~1.16)、1.34(1.18~1.51)、1.12(1.03~1.22)和2.21(1.51~3.24)]及碘營養(yǎng)水平缺乏是浙江省居民甲狀腺結(jié)節(jié)患病的危險因素。結(jié)論 2010年浙江省居民甲狀腺結(jié)節(jié)女性患病率高于男性,且隨年齡增長而逐漸升高;中老年人群應(yīng)是甲狀腺結(jié)節(jié)防治工作的重點對象;兒童甲狀腺結(jié)節(jié)患病率雖較低,但因為其發(fā)展為惡性的危險性高,應(yīng)引起重視;文化程度高、有食用海產(chǎn)品習(xí)慣、生氣頻率高、有甲狀腺疾病患病史、碘營養(yǎng)水平缺乏可能是人群甲狀腺結(jié)節(jié)發(fā)生的危險因素。
[Abstract]:Objective to investigate the prevalence and risk factors of thyroid nodules in Zhejiang Province. Methods the stratified cluster sampling method was used to select 22 counties and districts in Zhejiang Province from March to December 2010. A questionnaire survey was conducted among 18 956 permanent residents and foreigners living for more than 3 years (including general situation, life and eating habits). The incidence of thyroid nodules in different population in different areas was calculated, and the distribution level of factors related to thyroid nodules was described by detecting thyroid B ultrasound, water iodine, salt iodine, urinary iodine and so on. Logistic regression analysis was used to analyze the risk factors of thyroid nodules. Results the prevalence rate of thyroid nodules in Zhejiang Province was 21.78. The prevalence rate of thyroid nodules was 11.75 / 2227, which was higher than that of 10.03 / 1902 with multiple nodules (蠂 ~ 2 / 2 / 281.44 / P 0.05). The prevalence rate of thyroid nodules in men was 16.600.1324, which was lower than that in women's (25.592,795) (蠂 ~ 2 / 22 / 218.60 / P 0.05) and 23.622226 / 2 026 in urban residents. The number of people living in the countryside was 19.97% higher than that of the rural residents (蠂 2 / 922.53 / P 0.05), and all of them gradually increased with the increase of age (蠂 2 / 2 / 36.99 / P / 0.05; along the coast, The incidence of thyroid nodules in the coastal and inland areas was 25.05 and 18.52 respectively (25.05, 19.27 and 1343, respectively) and 18.52, 859 (蠂 ~ (2 +), 85.84, P 0.05), with a high level of education, frequent consumption of seafood, and high frequency of life, and the incidence of thyroid nodules in coastal and inland areas was higher than that in other regions, and the incidence of thyroid nodules in coastal and inland areas was 25.05 and 18.52, respectively. The history of thyroid disease [ORY95CII = 1.111.06 / 1.16 / 1.341.181.18 / 1.51 / 1.22] and iodine deficiency were risk factors of thyroid nodule in Zhejiang province. Conclusion the prevalence rate of thyroid nodules in Zhejiang Province in 2010 was higher than that in men, and the prevalence rate of thyroid nodules in children was low, and the prevalence rate of thyroid nodules in middle and old people should be the focus of the prevention and treatment of thyroid nodules. However, due to its high risk of malignancy, attention should be paid to its high level of education, high habit of edible seafood, high frequency of life, history of thyroid disease, and iodine deficiency may be the risk factors of thyroid nodule in the population.
【作者單位】： 浙江省疾病預(yù)防控制中心環(huán)境與職業(yè)衛(wèi)生所;
【基金】：浙江省科技廳重大專項(No.2009C03010-1)
【分類號】：R181.3;R581

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