本文選題：麻疹疫苗 + 強(qiáng)化免疫��； 參考：《吉林大學(xué)》2011年碩士論文

【摘要】：麻疹是嚴(yán)重威脅我國(guó)兒童健康的傳染病之一,是由麻疹病毒引起的急性、全身性、出疹性呼吸道傳染病。在發(fā)展中國(guó)家,麻疹在幼兒中的病死率可高達(dá)5%～10%。由于麻疹病毒只有一個(gè)血清型,抗原性非常穩(wěn)定,麻疹病毒不在動(dòng)物之間傳播,人是麻疹病毒的唯一宿主。因此使用有效安全的疫苗進(jìn)行預(yù)防,消除麻疹在理論層面和操作層面上都具有可行性。因此世界衛(wèi)生組織已將麻疹列為繼消滅天花、脊髓灰質(zhì)炎之后的第三個(gè)將要被消除或消滅的疾病。2006年我國(guó)所在的WHO西太區(qū)承諾在2012年消除麻疹,中國(guó)衛(wèi)生部下發(fā)了《2006—2012年中國(guó)消除麻疹行動(dòng)計(jì)劃》,我省按照衛(wèi)生部要求于2010年9月11-20日開(kāi)展全省范圍內(nèi)8月齡～6歲兒童的麻疹疫苗強(qiáng)化免疫活動(dòng)。本文通過(guò)對(duì)此次麻疹疫苗強(qiáng)化免疫活動(dòng)接種數(shù)據(jù)和在活動(dòng)中出現(xiàn)的疑似預(yù)防接種異常反應(yīng)數(shù)據(jù)的統(tǒng)計(jì)分析,對(duì)比強(qiáng)化免疫活動(dòng)前后一年時(shí)間吉林省麻疹的發(fā)病例數(shù)及發(fā)病率、其他省份及國(guó)家在此次強(qiáng)化免疫活動(dòng)中出現(xiàn)的疑似預(yù)防接種異常反應(yīng)情況,可以有效的評(píng)估吉林省這次全省范圍內(nèi)麻疹疫苗強(qiáng)化免疫活動(dòng)開(kāi)展效果,評(píng)價(jià)此次活動(dòng)麻疹疫苗接種安全性、疑似預(yù)防接種異常反應(yīng)發(fā)生的相關(guān)影響因素以及吉林省的疑似預(yù)防接種異常反應(yīng)監(jiān)測(cè)系統(tǒng)運(yùn)轉(zhuǎn)情況。為吉林省開(kāi)展消除麻疹行動(dòng)提供策略依據(jù)。
[Abstract]:Measles is one of the infectious diseases that seriously threaten the health of children in our country. It is an acute, systemic and rash respiratory infectious disease caused by measles virus. In developing countries, measles mortality in young children can be as high as 5 / 10. Because measles virus has only one serotype, antigenicity is very stable, measles virus does not spread between animals, human is the only host of measles virus. Therefore, the use of effective and safe vaccines for prevention and measles elimination is theoretically and operationally feasible. Therefore, the World Health Organization has listed measles as the third disease to be eliminated or eliminated after smallpox and polio. In 2006, our country's WHO West District pledged to eliminate measles by 2012. The Ministry of Health of China has issued the "China measles Elimination Action Plan 2006-2012". According to the requirements of the Ministry of Health, our province will carry out an intensified measles vaccination campaign for children aged 8 months or 6 years in the province from September 11 to 20, 2010. Based on the statistical analysis of the vaccination data of the measles vaccine intensive immunization campaign and the abnormal response data of suspected vaccination during the campaign, the number of measles cases and the incidence of measles in Jilin Province before and after the intensive immunization campaign were compared. The abnormal reactions of suspected vaccination in other provinces and countries in this intensive immunization campaign can effectively assess the effectiveness of the measles vaccine intensified immunization campaign in Jilin Province this time. To evaluate the safety of measles vaccination, the related factors of abnormal reaction of suspected vaccination, and the operation of abnormal response monitoring system of suspected vaccination in Jilin province. To provide strategic basis for carrying out measles elimination in Jilin province.
【學(xué)位授予單位】：吉林大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2011
【分類號(hào)】：R186

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