流感樣病例定義對(duì)流感監(jiān)測(cè)結(jié)果影響的比較分析
發(fā)布時(shí)間:2018-03-17 08:35
本文選題:流感 切入點(diǎn):人 出處:《中華疾病控制雜志》2017年09期 論文類型:期刊論文
【摘要】:目的比較不同臨床癥狀的流感樣病例流感檢出情況的差異,探討采用不同流感樣病例定義對(duì)流感監(jiān)測(cè)結(jié)果的影響。方法根據(jù)2015年上海市2家國(guó)家級(jí)流感監(jiān)測(cè)哨點(diǎn)醫(yī)院的流感病原學(xué)監(jiān)測(cè)數(shù)據(jù)和病例臨床癥狀,計(jì)算不同臨床癥狀(有咳嗽咽痛、僅咳嗽、僅咽痛)的流感樣病例流感病毒檢出情況,并通過(guò)多因素Logistic回歸分析流感病毒檢出情況的影響因素。結(jié)果 2 010例流感樣病例中,有咳嗽咽痛者1 105例、僅有咳嗽者270例、僅有咽痛者635例,流感陽(yáng)性率分別為36.2%、39.3%和15.9%,經(jīng)分析,有咳嗽咽痛者、僅有咳嗽者的流感陽(yáng)性檢出率均高于僅有咽痛者(均有P0.05)。對(duì)于發(fā)病3 d內(nèi)采樣的流感樣病例,有咳嗽咽痛、僅有咳嗽者的流感陽(yáng)性檢出率均高于僅咽痛者(均有P0.05)。多因素Logistic回歸分析結(jié)果顯示,流感病毒檢出情況與病例體溫(≥39℃)(OR=1.719,95%CI:1.389~2.127)、咳嗽(OR=3.046,95%CI:2.377~3.905)有關(guān)。結(jié)論建議以"發(fā)熱(體溫≥38℃)伴咳嗽癥狀者"作為流感監(jiān)測(cè)中的流感樣病例定義。
[Abstract]:Objective to compare the differences of influenza detection among patients with different clinical symptoms. To explore the effect of different flu-like case definitions on the results of influenza surveillance. Methods according to the data of influenza etiology surveillance and clinical symptoms of two national influenza surveillance sentinel hospitals in Shanghai in 2015. The detection of influenza virus in patients with different clinical symptoms (cough and pharynx, cough only and pharynx only) was calculated, and the influencing factors of influenza virus detection were analyzed by multivariate Logistic regression analysis. There were 1 105 cases with cough and pharynx, 270 cases with cough and 635 cases with sore throat. The positive rates of influenza were 39.3% and 15.9%, respectively. The positive rate of influenza in patients with cough was higher than that in patients with pharynx (P 0.05). The positive rate of influenza in patients with cough was higher than that in patients with pharynx only (P 0.05). Multivariate Logistic regression analysis showed that, The detection of influenza virus is related to the body temperature of the case (鈮,
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