本文關(guān)鍵詞： 多藥耐藥菌 醫(yī)院感染 干預(yù)措施　出處：《中華醫(yī)院感染學(xué)雜志》2017年12期 　論文類(lèi)型：期刊論文

【摘要】：目的了解多藥耐藥菌(MDRO)醫(yī)院感染情況,評(píng)價(jià)干預(yù)效果,為后期持續(xù)改進(jìn)提供理論依據(jù)。方法回顧性調(diào)查醫(yī)院2014年1月-2016年9月住院患者M(jìn)DRO醫(yī)院感染監(jiān)測(cè)結(jié)果,分析MDRO醫(yī)院感染流行病學(xué)特征,采取綜合干預(yù)措施,2014年1月-2015年5月數(shù)據(jù)為干預(yù)前組,共調(diào)查患者102 692例;2015年6月-2016年9月為干預(yù)后組,共調(diào)查患者97 577例,比較兩組患者M(jìn)DRO感染率,評(píng)價(jià)干預(yù)效果。結(jié)果 2014年1月-2016年9月年共監(jiān)測(cè)住院患者200 269例,共檢出MDRO 1 552株,其中院內(nèi)感染MDRO 449株,MDRO感染率為0.22%;不同性別、年齡患者感染率差異有統(tǒng)計(jì)學(xué)意義(P0.05);院內(nèi)感染MDRO致病菌前5位分別為鮑氏不動(dòng)桿菌(45.66%)、金黃色葡萄球菌(17.82%)、銅綠假單胞菌(17.37%)、肺炎克雷伯菌(14.25%)和大腸埃希菌(2.45%);科室分布以ICU為主(46.32%),其次為外科、內(nèi)科、新生兒與婦產(chǎn)科;季節(jié)分布呈現(xiàn)一、三季度高于二、四季度現(xiàn)象;通過(guò)采取綜合性干預(yù)措施,MDRO感染株數(shù)由267株下降至182株,感染發(fā)生率由基線期0.26%下降至干預(yù)期0.19%,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論采取有針對(duì)性綜合性干預(yù)措施,可有效降低多藥耐藥菌醫(yī)院感染的風(fēng)險(xiǎn),對(duì)保障醫(yī)療質(zhì)量與安全具有重要意義。
[Abstract]:Objective to investigate the nosocomial infection of multidrug resistant bacteria (MDR), evaluate the effect of intervention, and provide theoretical basis for continuous improvement in the later period. Methods the results of MDRO nosocomial infection surveillance in hospitalized patients from January 2014 to September 2016 were retrospectively investigated. The epidemiological characteristics of nosocomial infection in MDRO were analyzed and comprehensive intervention measures were taken. A total of 102,692 patients were investigated in the pre-intervention group from January 2014 to May 2015, and 97 577 patients in the post-intervention group from June 2015 to June 2015. Results from January 2014 to September 2016, a total of 200,269 MDRO strains were detected and 1 552 strains of MDRO were detected. The infection rate of MDRO 449 strains in hospital was 0.22%. The infection rate of age patients was significantly different (P 0.05), the top five pathogens of nosocomial infection of MDRO were Acinetobacter baumannii 45.66, Staphylococcus aureus 17.82, Pseudomonas aeruginosa 17.3737 and Klebsiella pneumoniae 14.255.The first five pathogens were Acinetobacter baumannii and Acinetobacter baumannii. ICU was the main part, and the second was surgery. Internal medicine, newborn and obstetrics and gynecology; seasonal distribution was higher in the first and third quarters than in the second and fourth quarters; the number of MDRO infection strains decreased from 267 to 182 through comprehensive intervention. The incidence of infection decreased from 0.26% in the baseline period to 0.19 in the dry period, the difference being statistically significant (P 0.05). Conclusion the risk of nosocomial infection caused by multidrug resistant bacteria can be effectively reduced by taking targeted comprehensive intervention measures, and it is of great significance to ensure the quality and safety of medical treatment.
【作者單位】： 連云港市第一人民醫(yī)院感染管理科;連云港市第一人民醫(yī)院質(zhì)量與安全管理辦公室;連云港市第一人民醫(yī)院微生物室;
【基金】：連云港市第一人民醫(yī)院青年英才豪森基金資助項(xiàng)目(QN160205)
【分類(lèi)號(hào)】：R181.3;R51

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