發(fā)布時(shí)間：2019-02-20 19:50

【摘要】：目的:通過(guò)分析細(xì)針吸取細(xì)胞學(xué)檢查(fine-needle aspiration cytology,FNAC)在頜面部常見(jiàn)脈管疾病診斷中準(zhǔn)確性、特異性,探討FNAC是否可作為頜面部脈管疾病鑒別診斷的常規(guī)方法。方法:采用回顧性研究的方法,對(duì)2011年11月至2014年9月在北京大學(xué)口腔醫(yī)院頜面外科激光整形美容門(mén)診就診的面部腫物患者按照納入標(biāo)準(zhǔn)和排除標(biāo)準(zhǔn)進(jìn)行篩選;提取入組病例的關(guān)鍵信息;根據(jù)治療方法分為手術(shù)組與非手術(shù)組,手術(shù)組以手術(shù)治療的術(shù)后病理結(jié)果為最終診斷依據(jù),非手術(shù)組以治療遠(yuǎn)期療效作為最終診斷依據(jù),判斷FNAC診斷口腔頜面部脈管疾病準(zhǔn)確性。結(jié)果:共納入病例93例,男性51例,女性42例,中位數(shù)年齡2.5歲。FNAC診斷脈管疾病結(jié)果為陽(yáng)性的病例67例,其中最終診斷符合脈管疾病63例,不符4例,診斷結(jié)果為陰性病例26例,符合脈管疾病5例,不符合脈管疾病21例,對(duì)脈管疾病診斷的敏感度為93%,特異度為84%;手術(shù)組29例,20例與病理結(jié)果相符合(69%),9例不符。誤診的9例最終病理結(jié)果包括脈管畸形3例,神經(jīng)纖維瘤2例,錯(cuò)構(gòu)瘤、皮脂腺囊腫、腺淋巴瘤、描述性診斷各1例。非手術(shù)組64例,61例與臨床診斷符合,3例不符合,不符合病例均為脈管畸形。FNAC結(jié)果與最終診斷結(jié)果總符合率為86%。結(jié)論:FNAC創(chuàng)傷小、結(jié)果回報(bào)快,對(duì)口腔頜面部常見(jiàn)脈管疾病具有輔助診斷的作用,可作為臨床篩查手段,具有一定臨床應(yīng)用價(jià)值。
[Abstract]:Objective: to analyze the accuracy and specificity of fine needle aspiration cytology (fine-needle aspiration cytology,FNAC) in the diagnosis of common vascular diseases in maxillofacial region and to explore whether FNAC can be used as a conventional method for differential diagnosis of vascular diseases in maxillofacial region. Methods: from November 2011 to September 2014, the patients with facial mass in the maxillofacial cosmetic clinic of Peking University Stomatology Hospital were screened according to the inclusive criteria and exclusion criteria. The key information of the cases was extracted. According to the treatment methods, the patients in the operation group were divided into two groups: the operative group and the non-operative group. The operative group took the postoperative pathological results as the final diagnostic basis, and the non-operative group took the long-term therapeutic effect as the final diagnostic basis. To determine the accuracy of FNAC in the diagnosis of vascular diseases in oral and maxillofacial regions. Results: a total of 93 cases (51 males and 42 females) were included. The median age was 2.5 years old. Among them, 63 cases were diagnosed as vascular diseases, and 4 cases were found to be inconsistent with the diagnosis of vascular diseases by FNAC. The diagnostic results were negative in 26 cases, in accordance with vascular diseases in 5 cases, and in nonconformity with vascular diseases in 21 cases. The sensitivity of diagnosis of vascular diseases was 933 and the specificity was 84. Of the 29 cases in the operation group, 20 cases were in agreement with the pathological results (69%), 9 cases were inconsistent. The final pathological results of 9 misdiagnosed cases included vascular malformation in 3 cases, neurofibroma in 2 cases, hamartoma, sebaceous cyst, adenomatous lymphoma, and descriptive diagnosis in 1 case each. In the non-operative group, 61 cases were in accordance with the clinical diagnosis, 3 cases were not in accordance with the clinical diagnosis, all the cases were vascular malformation. The total coincidence rate between the FNAC results and the final diagnosis results was 86g. Conclusion: FNAC has the advantages of small trauma and quick return. It is helpful for the diagnosis of common vascular diseases in oral and maxillofacial region. It can be used as a clinical screening method and has certain clinical application value.
【作者單位】： 北京大學(xué)口腔醫(yī)學(xué)院·口腔醫(yī)院口腔頜面外科口腔數(shù)字化醫(yī)療技術(shù)和材料國(guó)家工程實(shí)驗(yàn)室口腔數(shù)字醫(yī)學(xué)北京市重點(diǎn)實(shí)驗(yàn)室;首都醫(yī)科大學(xué)附屬北京友誼醫(yī)院病理科;
【分類號(hào)】：R782

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