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基于MRI的遼寧漢族成人顱面部三維重建及測量分析研究

發(fā)布時間:2018-10-24 19:10
【摘要】:目的 1.利用可重復測量的顱面部軟組織標志點,開發(fā)一種可靠的三維軟組織分析方法。 2.獲得遼寧漢族地區(qū)成年人正常顱面部三維軟組織形態(tài)的基本均值和各個部分的基本比例關(guān)系,為臨床醫(yī)學、法醫(yī)人類學提供基礎(chǔ)數(shù)據(jù)。 方法 采用GE超導1.5T MRI掃描儀對100例(女性50例,男性50例)遼寧漢族成人進行頭頸聯(lián)合掃描。納入標準:身體健康,發(fā)育正常,無面部畸形和瘢痕,上下頜牙齒排列整齊,牙與牙弓形態(tài)正常,顱頜關(guān)系協(xié)調(diào),磨牙為安氏Ⅰ類關(guān)系,,排除面部整形、正畸矯正、手術(shù)史及拍攝MRI禁忌的情況,年滿18歲。利用VGStduio2.2MAX軟件對掃描的DICOM格式的數(shù)據(jù)進行三維顱面重建,通過透明度及灰度值的調(diào)節(jié)以及恰當?shù)氖褂眠^濾器和表面測定,從而得到清晰的三維重建圖,配合三維的切面圖從而確定顱面部軟組織上53個標志點,獲得決定面部形態(tài)的10個角度。再將標志點的坐標通過WinEDMA1.0.1軟件獲取各標志點之間的距離共31項,建立51項水平、垂直向比例指數(shù)。測量結(jié)果經(jīng)SPSS17.0軟件包統(tǒng)計分析,并進行男性、女性兩組的t檢驗。 結(jié)果 1.通過MRI三維重建,實現(xiàn)顱面部軟組織三維測量,包括53個標志點,92項測量項目。顱面部測量的標志點間的距離共31項,男女之間差異有統(tǒng)計學意義的共有21項(P<0.05);角度測量共10項,有統(tǒng)計學意義的有2項(P<0.05);顱面部各部分的基本比例關(guān)系共有51項,有統(tǒng)計學意義的有14項(P<0.05)。 2.顱面部軟組織三維測量中,不夠準確的點主要涉及下頜角點、顴點和耳部的幾個標志點。本系統(tǒng)具有較高的精確度,滿足人體測量要求。 結(jié)論 1.基于MRI的顱面部軟組織三維測量系統(tǒng)可以作為一種可靠的三維軟組織分析方法。 2.遼寧地區(qū)漢族成年人正常顱面部形態(tài)的三維測量顯示:男、女之間的基本均值有明顯的差異;而各個部分的面部比例關(guān)系和角度測量差異并不大。我們還需要在以后的研究中對顱面部軟組織的三維信息做進一步的調(diào)查,以便于三維軟組織診斷與未來的治療方案和最終評價相結(jié)合。
[Abstract]:Objective 1. A reliable three dimensional soft tissue analysis method was developed by using the reproducible craniofacial soft tissue markers. 2. The basic mean value of normal craniofacial three-dimensional soft tissue morphology and the basic proportion of each part were obtained in the Han nationality area of Liaoning Province, which provided the basic data for clinical medicine and forensic anthropology. Methods GE superconducting 1.5T MRI scanner was used to scan the head and neck of 100 Han nationality adults (50 female and 50 male). Inclusion criteria: healthy, normal development, no facial deformities and scars, regular arrangement of upper and lower teeth, normal shape of teeth and dental arch, coordination of craniomandibular relationship, molars of class I relationship, exclusion of facial plastic, orthodontic correction, History of surgery and contraindications for photographing MRI, aged 18 years or older. The 3D craniofacial reconstruction of scanned DICOM data was carried out by using VGStduio2.2MAX software. By adjusting the transparency and gray value and using filter and surface measurement appropriately, a clear 3D reconstruction image was obtained. In order to determine 53 mark points on craniofacial soft tissue, 10 angles of facial morphology were obtained. Then the coordinates of the mark points are obtained by WinEDMA1.0.1 software, the distance between the markers is 31 items, and 51 items of horizontal and vertical proportional indices are established. The results were statistically analyzed by SPSS17.0 software package, and t-test was carried out in two groups: male and female. Result 1. The 3D measurement of craniofacial soft tissue was realized by MRI reconstruction, including 53 markers and 92 items. The distance between the markers of craniofacial measurement was 31, the difference between men and women was statistically significant (P < 0.05), the angle measurement was 10, there were 2 (P < 0.05). There were 51 items of basic proportion relationship between craniofacial parts and 14 items of statistical significance (P < 0.05). 2. In the 3D measurement of craniofacial soft tissue, the inaccurate points mainly involve the mandibular corner, zygomatic point and several mark points of the ear. The system has high accuracy and meets the requirements of anthropometry. Conclusion 1. The three dimensional measurement system of craniofacial soft tissue based on MRI can be used as a reliable three dimensional soft tissue analysis method. 2. Three-dimensional measurement of normal craniofacial morphology of Han nationality adults in Liaoning province showed that there were obvious differences in the basic mean values between men and women, but there was no significant difference in facial proportions and angles between different parts of the population. We also need to further investigate the three-dimensional information of craniofacial soft tissue in future studies so as to facilitate the integration of 3D soft tissue diagnosis with future treatment and final evaluation.
【學位授予單位】:遼寧醫(yī)學院
【學位級別】:碩士
【學位授予年份】:2014
【分類號】:R783.5

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