【摘要】：目的研究種植體支抗后牽引矯形力作用下上頜骨相關(guān)骨縫改建特點(diǎn),探討后牽引抑制上頜骨生長的作用機(jī)制。方法選用青春生長發(fā)育期的雄性恒河猴4只,隨機(jī)分為3組(1.5月組1只、3月組2只和對照組1只)。實(shí)驗(yàn)組在其顴骨體部植入微鈦板種植體,上頜佩戴全牙弓夾板,以單側(cè)150g力的Ni-Ti螺旋拉簧連接上述部分,方向與平面平行,建立了顴骨種植體支抗后牽引上頜骨動物模型。采用組織學(xué)蘇木精-伊紅染色及計(jì)算機(jī)組織形態(tài)測定技術(shù),定量分析骨縫反應(yīng)的變化情況。結(jié)果骨縫寬度:在后牽引力作用下,顴頜縫、翼腭縫、橫腭縫和顴顳縫骨縫寬度減小;腭中縫、額頜縫、蝶顴縫和顴額縫骨縫寬度增大。其中,額頜縫、蝶顴縫3月組增加較為明顯,1.5月組與對照組相比差異無統(tǒng)計(jì)學(xué)意義;而顴顳縫、翼腭縫1.5月組減小較為明顯,但與3月組比較差異無統(tǒng)計(jì)學(xué)意義。細(xì)胞密度:在后牽引力作用下,1.5月組各骨縫細(xì)胞密度均增大,隨著牽引時(shí)間延長,顴頜縫、翼腭縫、橫腭縫和顴顳縫細(xì)胞密度減小,呈現(xiàn)出壓縮效應(yīng);腭中縫、額頜縫、蝶顴縫和顴額縫細(xì)胞密度增大,呈現(xiàn)出牽張效應(yīng),結(jié)果與骨縫寬度變化一致。但是隨著牽引時(shí)間的進(jìn)一步延長,骨縫的細(xì)胞密度變化略有差異。顴頜縫、翼腭縫、腭中縫和額頜縫1.5月組與3月組相比差異無統(tǒng)計(jì)學(xué)意義。結(jié)論后牽引力作用下,上頜骨有向后壓縮并伴順時(shí)針旋轉(zhuǎn)趨勢,顴骨作為支抗承載骨也有一定的旋轉(zhuǎn)趨勢。與正中矢狀面有一定夾角的后牽引力對上頜腭中縫有橫向擴(kuò)弓的效應(yīng)。
[Abstract]:Objective to study the remodeling characteristics of maxillary associated suture under orthopedic force of implant Anchorage, and to explore the mechanism of posterior traction on the inhibition of maxillary growth. Methods four male rhesus monkeys were randomly divided into 3 groups (1. 5 month group, 2 3 months group and 1 control group). In the experimental group, microtitanium plate implants were implanted in the zygomatic body and the maxillary arch splint was worn. The animal model of maxillary traction was established by using a Ni-Ti helical pull spring with a unilateral force of 150g. The direction was parallel to the plane. Histopathological hematoxylin-eosin staining and computer histomorphometry were used to quantitatively analyze the changes of bone suture reaction. Results width of suture: the width of zygomatigomaxillary suture, pterygopalatine suture, transverse palatine suture and zygomaticotemporal suture decreased, and the width of palatine middle suture, frontomaxillary suture, sphenozygomatic suture and zygomatic frontal suture increased. Among them, the frontal and maxillary suture and sphenozygomatic suture increased significantly in 3 months group, but there was no significant difference between 1.5 month group and control group, but the decrease of zygomaticotemporal suture and pterygopalatine suture 1.5 month group was more obvious, but there was no significant difference compared with 3 month group. Cell density: under the action of posterior traction, the cell density of bone suture increased in 1.5 months group. With the extension of traction time, the cell density of zygomatigomaxillary suture, pterygopalatine suture, transverse palatine suture and zygomatic-zygomatic suture decreased. The density of sphenozygomatic suture and zygomatic frontal suture increased, showing the effect of distraction, and the results were consistent with the width of bone suture. However, with the further extension of traction time, the cell density of bone suture changed slightly. There was no significant difference in zygomatigomaxillary suture, pterygopalatine suture, palatine suture and frontomaxillary suture 1.5 months compared with 3 months group. Conclusion the maxillary bone has the tendency of backward compression and clockwise rotation under the action of posterior traction, and the zygomatic bone as the Anchorage bearing bone has a certain tendency of rotation. The posterior traction with a certain angle to the median sagittal plane has the effect of transverse expansion of the maxillary palatine suture.
【作者單位】： 四川省自貢市第四人民醫(yī)院口腔科;昆明醫(yī)科大學(xué)附屬口腔醫(yī)院正畸科;
【基金】：國家自然科學(xué)基金資助項(xiàng)目(No.81060089)
【分類號】：R783.5

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