【摘要】：目的:本研究擬通過共振頻率分析法結(jié)合組織學觀察評價延期加載正畸牽引力對微種植體穩(wěn)定性及周圍骨組織改建的影響。方法:選用12只雄性新西蘭兔,將48枚微種植體(AbsoAnchor,Dentos,Korea)植入于雙側(cè)兔脛骨內(nèi),每側(cè)脛骨各植入兩枚。植入后28天每側(cè)兩個微種植體間放置鎳鈦拉簧,右側(cè)加載180g牽引力,左側(cè)不加力。動物分別于植入后31天、35天、42天及56天處死(n=3)。在植入、加載及動物處死時對所有微種植體進行共振頻率分析,測量種植體穩(wěn)定性系數(shù)(ISQ),采用配對t檢驗比較加載組與非加載組的差異。對所有標本脫鈣切片后進行組織學觀察。結(jié)果:(1)非加載側(cè)微種植體在植入后31天種植體-骨界面呈現(xiàn)為大量的編織骨,56天時新生骨改建成熟為致密的板層骨。加載側(cè)與非加載側(cè)相比在植入后31天、35天、42天和56天各時間點的骨組織改建未見明顯差異。(2)共振頻率分析顯示,微種植體植入后ISQ值逐漸升高,加載側(cè)及非加載側(cè)在植入當天的ISQ值分別為20.40±2.87和20.98±3.17;植入后56天ISQ值升高至39.50±2.05和36.33±2.30。加載組和非加載組在各時間點ISQ值均無統(tǒng)計學差異(P0.05)。結(jié)論:微種植體植入28天后加載180g牽引力對微種植體穩(wěn)定性和周圍骨組織改建無影響。
[Abstract]:Aim: to evaluate the effects of delayed loading orthodontic traction on the stability of microimplants and the remodeling of bone tissue around microimplants by means of resonance frequency analysis (RFA) and histological observation. Methods: twelve male New Zealand rabbits were selected and 48 microimplants (AbsoAnchor,Dentos,Korea) were implanted into bilateral tibia. On the 28th day after implantation, Ni-Ti tension spring was placed between two microimplants on each side, 180 g traction was loaded on the right side and no additional force was applied on the left side. The animals were killed 31 days, 35 days, 42 days and 56 days, respectively. Resonance frequency analysis was performed on all microimplants during implantation, loading and animal execution. The stability coefficient of implants was measured by (ISQ),. The difference between the loaded group and the non-loaded group was compared by paired t test. Histological observation was performed on all specimens after decalcification. Results: (1) on the 31st day after implantation, the implant-bone interface of the unloaded microimplants presented as a large number of braided bone at 56 days after implantation, the new bone remodeled and matured into a dense lamellar bone. There was no significant difference in bone tissue remodeling between the loading side and the non-loaded side at the 31d, 35d, 42nd and 56d after implantation. (2) Resonance frequency analysis showed that the ISQ value increased gradually after microimplant implantation. The ISQ values of the loading side and the non-loading side were 20.40 鹵2.87 and 20.98 鹵3.17 on the day of implantation, respectively, and the ISQ values increased to 39.50 鹵2.05 and 36.33 鹵2.30 on the 56th day after implantation. There was no significant difference in ISQ between the loading group and the non loading group at each time point (P0.05). Conclusion: after 28 days of microimplant implantation, 180 g tractive force has no effect on the stability of microimplant and bone tissue remodeling.
【學位授予單位】：上海交通大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R783.5

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