發(fā)布時(shí)間：2018-06-21 13:41

  本文選題：雙黃補(bǔ) + 玉米醇溶蛋白��； 參考：《中國(guó)現(xiàn)代醫(yī)學(xué)雜志》2014年24期

【摘要】：目的探討牙齦成纖維細(xì)胞-玉米醇溶蛋白支架-雙黃補(bǔ)復(fù)合體對(duì)牙周組織修復(fù)的作用。方法以2只Beagle犬雙側(cè)上頜、下頜,共24個(gè)牙位制備牙周缺損模型,將其分為四組,每組6個(gè)牙位:玉米醇溶蛋白支架組;牙齦成纖維細(xì)胞-玉米醇溶蛋白支架復(fù)合體組;牙齦成纖維細(xì)胞-玉米醇溶蛋白支架-雙黃補(bǔ)復(fù)合體組;空白對(duì)照組,分別于術(shù)后3個(gè)月進(jìn)行組織學(xué)及掃描電鏡觀察。結(jié)果術(shù)后3個(gè)月,牙齦成纖維細(xì)胞-玉米醇溶蛋白支架-雙黃補(bǔ)復(fù)合體組組織學(xué)觀察可見(jiàn)新生牙槽骨內(nèi)見(jiàn)趨于成熟的哈弗氏系統(tǒng),且生長(zhǎng)高度為(1.340±0.020)mm,顯著高于其余三組新生牙槽骨高度(P0.05)。掃描電鏡下,牙齦成纖維細(xì)胞-玉米醇溶蛋白質(zhì)支架-雙黃補(bǔ)復(fù)合體組牙槽骨可見(jiàn)趨于成熟的哈弗氏系統(tǒng),而牙齦成纖維細(xì)胞-玉米醇溶蛋白質(zhì)支架組及玉米醇溶蛋白質(zhì)支架組僅可見(jiàn)排列紊亂的骨小梁結(jié)構(gòu),空白對(duì)照組僅可見(jiàn)纖維性成骨。結(jié)論中藥雙黃補(bǔ)可促進(jìn)新生牙槽骨生長(zhǎng),利于牙周組織的修復(fù)。
[Abstract]:Objective to investigate the effect of gingival fibroblasts - zein Stents - double yellow patch on periodontal tissue repair. Methods the periodontal defect models were made in 2 Beagle dogs, bilateral maxillary, mandibular and 24 teeth, and were divided into four groups of 6 teeth in each group: gingival fibroblast cells - zein stents In the complex group, gingival fibroblasts - zein Stents - double yellow complex group and blank control group, histological and scanning electron microscopy were observed at 3 months after the operation. Results the histological observation of gingival fibroblasts - zein Stents - double yellow complement group showed that the new alveolar bone tended to mature in the 3 months after the operation. The hover system, with a height of (1.340 + 0.020) mm, was significantly higher than the rest of the other three groups of newborn alveolar bone (P0.05). Under scanning electron microscopy, the gingival fibroblasts - the gingival soluble protein scaffold and the double yellow complement group could see the mature Haversian system, and the gingival fibroblasts - the corn alcohol soluble protein scaffold group and the gingival fibroblasts and the gingival fibroblasts The structure of the bone trabecula in the group of corn alcohol soluble protein scaffolds was only visible, and the blank control group was only visible with fibrous osteogenesis. Conclusion double yellow supplement can promote the growth of new alveolar bone and be beneficial to the repair of periodontal tissue.
【作者單位】： 河北醫(yī)科大學(xué)第四醫(yī)院口腔科;
【基金】：國(guó)家自然科學(xué)基金面上項(xiàng)目(No:30873289)
【分類號(hào)】：R781.4
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本文編號(hào)：2048850