本文選題：等離子體電解氧化 + 鋅��； 參考：《上�？谇会t(yī)學(xué)》2014年05期

【摘要】：目的:利用等離子體電解氧化技術(shù),在純鈦表面制備不同鋅含量的鈣磷活性涂層,比較純鈦表面不同鋅含量活性涂層的理化性能差異及其對(duì)牙齦卟啉單胞菌(P.gingivalis,Pg)及伴放線放線桿菌(A.actinomycetemcomitans,Aa)抗菌性能的影響。方法:在等離子體電解氧化的電解液中,每組各加入0.08 mol/L鈣和0.06 mol/L磷,再分別向各組加入0.01、0.03、0.05 mol/L鋅處理純鈦片,制成低、中、高3種不同鋅含量的鈣磷活性涂層,以不加鋅組作為對(duì)照組。利用電子萬(wàn)能測(cè)試機(jī)檢測(cè)涂層與鈦基底的結(jié)合力,掃描電鏡(SEM)觀察鈦片表面形貌,X線衍射(XRD)分析材料表面晶相結(jié)構(gòu),X射線光電子能譜儀(XPS)分析材料表面化學(xué)組成及元素成分。材料表面培養(yǎng)Pg和Aa后,應(yīng)用掃描電鏡和貼膜法評(píng)價(jià)鋅含量與抗菌性能的關(guān)系。采用SPSS13.0軟件包對(duì)數(shù)據(jù)進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果:隨著鋅含量的提高,涂層的孔徑及粗糙度隨之增加;低鋅組結(jié)晶優(yōu)于高鋅組;低鋅組HA和Zn3P2含量較多,高鋅組ZnO含量多。掃描電鏡觀察,隨著鋅含量的提高,材料表面Pg和Aa細(xì)菌數(shù)量逐漸減少,高鋅組部分細(xì)菌出現(xiàn)裂解、壞死。通過(guò)貼膜法觀察,隨著鋅含量的提高,材料表面Pg和Aa細(xì)菌數(shù)量逐漸減少,且4組間差異顯著。結(jié)論:鋅含量的變化會(huì)改變涂層的理化性能。高含量鋅的鈣磷涂層,抗菌性能最佳。
[Abstract]:Objective: to prepare calcium-phosphorus active coatings with different zinc content on pure titanium by plasma electrolytic oxidation. To compare the physical and chemical properties of the active coatings with different zinc content on pure titanium and their effects on the antibacterial properties of P.gingivalis Pg and A. actinomycetemcomitansa) of P.gingivalis (P.gingivalis) and A. actinomycetemcomitansa (A. actinomycetemcomitansa). Methods: in each group, 0.08 mol / L calcium and 0.06 mol / L phosphorus were added to the electrolytic solution of plasma electrolytic oxidation, and 0.01g 0.03 渭 mol / L zinc was added to each group to treat pure titanium sheet, and three kinds of calcium and phosphorus active coatings with low, medium and high zinc content were prepared. The control group was treated with no zinc. The adhesion between the coating and the titanium substrate was tested by the electronic universal tester. The surface morphology of the titanium sheet was observed by scanning electron microscopy (SEM) and the X-ray diffraction (XRD) was used to analyze the crystal phase structure and X-ray photoelectron spectroscopy (XPS) of the material surface. The chemical composition and elemental composition of the material were analyzed by X-ray photoelectron spectroscopy (XPS). The relationship between zinc content and antibacterial activity was evaluated by scanning electron microscopy (SEM) and film sticking method after surface culture of PG and AA. SPSS 13.0 software package was used to analyze the data. Results: with the increase of zinc content, the pore diameter and roughness of the coating increased, the crystallization of low zinc group was better than that of high zinc group, the HA and Zn3P2 contents of low zinc group were more than that of high zinc group, and that of high zinc group was more than that of high zinc group. SEM observation showed that with the increase of zinc content, the number of PG and AA bacteria on the surface of the materials gradually decreased, and some bacteria in high zinc group were cracked and necrotized. With the increase of zinc content, the amount of PG and AA bacteria on the surface of the materials gradually decreased, and the differences among the four groups were significant. Conclusion: the change of zinc content will change the physical and chemical properties of the coating. Calcium and phosphorus coatings with high zinc content have the best antibacterial properties.
【作者單位】： 中國(guó)醫(yī)科大學(xué)附屬口腔醫(yī)院;中國(guó)科學(xué)技術(shù)研究院金屬腐蝕所;
【基金】：沈陽(yáng)市科學(xué)技術(shù)計(jì)劃項(xiàng)目(F11-264-1-25) 遼寧省科學(xué)技術(shù)計(jì)劃項(xiàng)目(2013225049) 中國(guó)醫(yī)科大學(xué)口腔醫(yī)學(xué)院青年科研啟動(dòng)基金(K101593-14-45)~~
【分類號(hào)】：R783.1

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本文編號(hào)：1994779