本文選題：位點保存 + 富血小板纖維蛋白��； 參考：《中國口腔種植學(xué)雜志》2017年03期

【摘要】：目的:觀察富血小板血纖維蛋白(PRF)復(fù)合引導(dǎo)骨再生(GBR)技術(shù)在牙槽嵴位點保存中的應(yīng)用效果及骨再生情況。方法:選取本院口腔科就診上前牙外傷患者5例,分為對照組和實驗組,二組分別為同一患者雙側(cè)對稱同名牙,實驗組行PRF膜+Bio-Oss骨粉+海奧生物膜位點保存術(shù),對照組行Bio-Oss骨粉+海奧生物膜位點保存術(shù)。術(shù)后2周、4周、6周、8周、12周X線片應(yīng)用MATLAB軟件進行術(shù)區(qū)灰度值測量,術(shù)后半小時、6周及12周錐形束CT(CBCT)應(yīng)用simplant軟件行牙槽嵴頂下2mm、4mm、6mm三個位點牙槽骨寬度、高度及術(shù)區(qū)骨質(zhì)密度測量。結(jié)果:二組X線片灰度值差異有統(tǒng)計學(xué)意義(P0.01),二組各時期X線片灰度值的差值差異均有統(tǒng)計學(xué)意義(P0.01),相關(guān)性檢驗示與時間有相關(guān)性(P0.01),二組術(shù)后即刻及術(shù)后12周牙槽嵴頂下2mm、4mm、6mm寬度、牙槽嵴頂?shù)綄︻M牙切端平面高度差異無統(tǒng)計學(xué)意義(P0.05),CBCT術(shù)區(qū)骨密度值差異有統(tǒng)計學(xué)意義(P0.05),相關(guān)性檢驗示與時間有相關(guān)性(P0.01)。結(jié)論:PRF配合GBR技術(shù)與單純使用GBR技術(shù)進行位點保存術(shù)均能有效減少牙拔除術(shù)后牙槽骨寬度及高度的吸收,并且PRF可以促進新骨生成以及人工骨粉向新骨轉(zhuǎn)化,同時期較單純GBR技術(shù)成骨速度快。
[Abstract]:Objective: to observe the effect of platelet rich blood fibrin (PRF) combined with guided bone regeneration (GBR) technique in alveolar ridge preservation and bone regeneration. Methods: five patients with anterior teeth trauma were divided into two groups: control group and experimental group. The two groups were bilateral symmetric teeth of the same patient. The experimental group was treated with PRF membrane Bio-Oss bone powder sea auricle biofilm site preservation. The control group was treated with Bio-Oss bone powder, sea auricle biofilm site preservation. The gray value of the operation area was measured by MATLAB software. The width of alveolar bone was measured by simplant software at 2 mm, 4 mm and 6 mm below the top of alveolar crest with simplant software at 6 weeks and 12 weeks after operation, and the width of alveolar bone at 3 sites was measured by MATLAB software in the second week, 4 weeks, 8 weeks, and 12 weeks after operation, and the width of alveolar bone was measured by simplant software. Height and bone density were measured. Results: there was significant difference in gray value of X-ray film between the two groups (P 0.01). The difference of gray value of X ray film in two groups was statistically significant (P 0.01). The correlation test showed that there was a correlation with time (P 0.01). The teeth of both groups were immediately after operation and 12 weeks after operation. The width of the alveolar ridge was 4 mm and 6 mm below the top of the alveolar ridge. There was no significant difference between the top of alveolar ridge and the height of the incisal end of maxillary teeth. There was significant difference in bone mineral density (BMD) between CBCT and P0.05. The correlation test showed that there was a correlation between BMD and time. Conclusion GBR combined with GBR and GBR can effectively reduce the width and height of alveolar bone resorption, and PRF can promote the formation of new bone and the transformation of artificial bone powder to new bone. At the same time, the rate of osteogenesis was faster than that of GBR alone.
【作者單位】： 山西醫(yī)科大學(xué)口腔醫(yī)學(xué)系;山西醫(yī)科大學(xué)第一醫(yī)院口腔科;
【分類號】：R783.6

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