本文選題：牙周炎 + 動(dòng)脈粥樣硬化��； 參考：《口腔醫(yī)學(xué)研究》2016年06期

【摘要】：目的:通過對(duì)冠心病住院患者進(jìn)行問卷調(diào)查和口腔檢查,初步探討牙周炎與動(dòng)脈粥樣硬化之間的相關(guān)性。方法:選擇經(jīng)病史和冠狀動(dòng)脈造影確診為冠心病的患者,詳細(xì)記錄其人口特征、血壓、糖尿病病史、心血管病史、血脂系列結(jié)果以及口腔情況。頸動(dòng)脈超聲檢測(cè)頸動(dòng)脈內(nèi)中膜厚度(carotid artery intima-media thickness,CIMT)及斑塊情況。結(jié)果:非條件Logistic回歸分析結(jié)果顯示缺牙數(shù)目與斑塊發(fā)生存在正相關(guān)(OR=1.298,95%CI:1.100-1.531,P=0.002);簡單線性回歸分析結(jié)果顯示缺牙數(shù)目與CIMT存在線性關(guān)系,回歸系數(shù)b=0.041。缺牙數(shù)目與斑塊直徑之間存在相關(guān)關(guān)系,相關(guān)系數(shù)rs=0.519,P0.001。缺牙數(shù)目與血脂各項(xiàng)指標(biāo)之間無統(tǒng)計(jì)學(xué)意義。結(jié)論:對(duì)于本研究人群(冠心病住院患者),隨著缺牙數(shù)目的增加,頸動(dòng)脈斑塊的發(fā)生率增加,頸動(dòng)脈內(nèi)中膜厚度及斑塊的大小也增加,這表明牙周炎導(dǎo)致的牙齒缺失可能是動(dòng)脈粥樣硬化疾病的一個(gè)重要的風(fēng)險(xiǎn)指標(biāo)。
[Abstract]:Objective: To investigate the correlation between periodontitis and atherosclerosis by questionnaire and oral examination of the patients in the patients with coronary heart disease. Methods: select patients with coronary heart disease diagnosed by medical history and coronary angiography, and record their demographic characteristics, blood pressure, history of glucose and urine, cardiovascular history, blood lipid series and mouth. Cavities. Carotid artery ultrasound (carotid artery intima-media thickness, CIMT) and plaque were detected by carotid artery ultrasound. Results: the results of non conditional Logistic regression analysis showed that there was a positive correlation between the number of teeth missing and the occurrence of plaque (OR=1.298,95%CI:1.100-1.531, P=0.002), and the results of simple linear regression analysis showed the number of teeth missing and CIMT. There is a linear relationship. There is a correlation between the number of teeth missing and the diameter of plaque b=0.041.. There is no statistical significance between the correlation coefficient rs=0.519, the number of P0.001. teeth missing and the indexes of blood lipid. Conclusion: the incidence of carotid plaque increases with the increase of the number of tooth deficiency in this study group. The intima media thickness and plaque size also increased, indicating that tooth loss caused by periodontitis may be an important risk indicator for atherosclerotic disease.
【作者單位】： 山西醫(yī)科大學(xué)口腔醫(yī)學(xué)系;
【基金】：國家自然科學(xué)基金項(xiàng)目(編號(hào):81271144、31050002)
【分類號(hào)】：R541.4;R781.42

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