本文選題：純鈦 + 微弧氧化��； 參考：《佳木斯大學》2017年碩士論文

【摘要】：目的:為改善純鈦種植體的生物學性能,對其表面進行超聲微弧氧化-多巴胺-杜仲提取物復合處理,探討純鈦微弧氧化載杜仲提取物生物膜層對金黃色葡萄球菌、大腸桿菌及成骨細胞生物相容性的影響,為其臨床應用提供參考和依據(jù)。方法:純鈦微弧氧化-多巴胺為A組,用以對照。純鈦微弧氧化-多巴胺-載0.003125g/ml、0.00625g/ml、0.009375g/ml杜仲提取物復合處理依次為實驗B、C、D組。純鈦微弧氧化-多巴胺-載杜仲提取物復合處理試件與金黃色葡萄球菌、大腸桿菌37℃恒溫箱內培養(yǎng),覆膜法檢測抗菌性;采用CCK-8法,SEM,ALP法檢測試件的細胞相容性。結果:C、D兩組具有較強的抗菌性。CCK-8與ALP分析表明,實驗組試件表面相比對照組更有利于細胞的粘附與增殖,順序為CDBA,四組均有統(tǒng)計學意義。激光共聚焦細胞骨架形態(tài)學顯示C、D兩組更利于細胞的鋪展和交聯(lián)。結論:四組材料均有良好的生物相容性,且C組純鈦微弧氧化-多巴胺-0.00625g/ml杜仲提取物生物相容性最佳。
[Abstract]:Objective: to improve the biological properties of pure titanium implants, the surface of the implants was treated with ultrasonic micro-arc oxidation and dopamine-Eucommia ulmoides extract, and the biofilm of pure titanium microarc oxidation containing eucommia ulmoides extract was studied for staphylococcus aureus.The effect of Escherichia coli and osteoblast biocompatibility provides reference and basis for its clinical application.Methods: pure titanium microarc oxidation-dopamine was used as control group.Pure titanium microarc oxidation-dopamine loaded 0.003125g / ml 0.00625g / ml 0.009375g / ml Eucommia ulmoides extract compound treatment followed by the experimental group BCU D.Pure titanium microarc oxidation-dopamine-loaded Eucommia ulmoides extract was cultured with Staphylococcus aureus and incubated in E. coli at 37 鈩，

本文編號：1748316