【摘要】：目的探討兒童孤獨(dú)癥發(fā)病的相關(guān)危險(xiǎn)因素,為孤獨(dú)癥的防治提供理論依據(jù)。方法采用成組病例對(duì)照研究,對(duì)165例孤獨(dú)癥兒童和320例正常對(duì)照組兒童,采用自編的孤獨(dú)癥危險(xiǎn)因素調(diào)查表收集相關(guān)危險(xiǎn)因素、家庭一般情況等資料,用χ2檢驗(yàn)分析兩組兒童之間危險(xiǎn)因素的差異。結(jié)果病例組母親高生育年齡(≥35歲)、有人工流產(chǎn)史、母孕期抑郁情緒史、母孕期被動(dòng)吸煙史及父親內(nèi)向所占比例較正常組高(P0.05),進(jìn)一步進(jìn)行Logistic回歸分析顯示母高育齡、孕期抑郁情緒、孕期被動(dòng)吸煙、有人工流產(chǎn)史以及父親性格內(nèi)向?yàn)楣陋?dú)癥的危險(xiǎn)因素。結(jié)論母親高齡生育、有人工流產(chǎn)史、孕期抑郁情緒、孕期被動(dòng)吸煙以及父親性格內(nèi)向均可使兒童孤獨(dú)癥發(fā)病風(fēng)險(xiǎn)增高。
[Abstract]:Objective to explore the risk factors of autism in children and to provide theoretical basis for the prevention and treatment of autism. Methods 165 autistic children and 320 normal control children were studied by a case-control study. The self-designed questionnaire on risk factors of autism was used to collect relevant risk factors, family general situation and so on. The difference of risk factors between the two groups was analyzed by 蠂 2 test. Results the proportion of mothers with high childbearing age (鈮，

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