伴抑郁情緒內(nèi)科門診患者的血管內(nèi)皮功能
發(fā)布時(shí)間:2018-12-10 08:32
【摘要】:目的:探討內(nèi)科門診患者的抑郁情緒與血管內(nèi)皮功能的關(guān)系。方法:采用橫斷面調(diào)查,選取就診于三甲綜合醫(yī)院內(nèi)科門診,漢密頓抑郁量表17項(xiàng)評分≥17分和臨床總體印象評分≥4分的63例患者作為伴抑郁情緒組,選取漢密頓抑郁量表17項(xiàng)評分7分、漢密頓焦慮量表評分≤6分、臨床總體印象評分≤2分的63例患者作為無抑郁情緒組,兩組年齡與體質(zhì)量指數(shù)均匹配。調(diào)查患者是否存在冠心病、糖尿病、腦梗死病史,并對血糖、血脂、血壓指標(biāo)進(jìn)行測查,采用Endo-PAT2000檢測儀評估內(nèi)皮功能指數(shù)(RHI)。結(jié)果:多重線性回歸分析結(jié)果顯示,RHI水平與伴抑郁情緒呈負(fù)向關(guān)聯(lián)(β'=-0.31,P0.001)。按有/無冠心病病史分層分析伴抑郁情緒與RHI水平的關(guān)系,有冠心病病史的患者中,伴抑郁情緒者(n=28)與無抑郁情緒組(n=22)的RHI差異無統(tǒng)計(jì)學(xué)意義[(1.8±0.5)vs.(1.8±0.7),P0.05];無冠心病病史的患者中,伴抑郁情緒者(n=47)的RHI水平低于無抑郁情緒者(n=53)[(2.1±0.6)vs.(2.4±0.6),P0.05]。結(jié)論:內(nèi)科門診抑郁情緒患者可能存在內(nèi)皮功能障礙。
[Abstract]:Objective: to investigate the relationship between depression and vascular endothelial function in outpatients. Methods: a cross-sectional survey was carried out in 63 patients with depression in the outpatient department of Department of Internal Medicine, Hamilton Depression scale (17 items 鈮,
本文編號:2370286
[Abstract]:Objective: to investigate the relationship between depression and vascular endothelial function in outpatients. Methods: a cross-sectional survey was carried out in 63 patients with depression in the outpatient department of Department of Internal Medicine, Hamilton Depression scale (17 items 鈮,
本文編號:2370286
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