腦干卒中患者的認(rèn)知障礙研究
發(fā)布時間:2018-11-25 22:42
【摘要】:目的研究急性孤立性腦干卒中患者認(rèn)知功能與正常對照之間的差異,探究腦干卒中對認(rèn)知功能的影響及其主要受損的認(rèn)知域。方法選取符合入組標(biāo)準(zhǔn)的、性別、年齡和受教育年限匹配的首次發(fā)病的急性孤立性腦干卒中患者29例和正常對照20例,分別進行艾登布魯克斯認(rèn)知檢測(ACE-Ⅲ)、蒙特利爾認(rèn)知評估量表(MoCA)、數(shù)字符號轉(zhuǎn)換測驗(SDMT)、韋氏數(shù)字廣度測驗(DS)、連線測驗(TMT)、Stroop詞色測驗等量表評測及事件相關(guān)電位P300檢測。結(jié)果腦干卒中患者MoCA量表和ACE-Ⅲ量表總體評分與對照組相比顯著降低(P=0.012,P=0.004),其中受損的認(rèn)知域主要為語言功能(P=0.024)及視空間功能(P=0.004)。SDMT、DS、TMT和Stroop等量表完成度欠佳,與對照組相比,均未見顯著差異(P0.05)。P300檢測結(jié)果顯示腦干卒中患者較對照組存在顯著的波幅降低(P=0.022)及潛伏期延長(P=0.033)。ACE-Ⅲ與MoCA顯著正相關(guān)(P0.001),而與P300潛伏期顯著負(fù)相關(guān)(P=0.006)。結(jié)論急性孤立性腦干卒中患者存在一定的認(rèn)知功能障礙,受損的認(rèn)知域主要為注意力、語言及視空間能力。
[Abstract]:Objective to study the difference between cognitive function and normal control in patients with acute isolated brainstem stroke, and to explore the effect of brainstem stroke on cognitive function and its main impaired cognitive domain. Methods A total of 29 patients with acute isolated brainstem stroke and 20 normal controls who matched sex, age and years of education were selected to perform ACE- 鈪,
本文編號:2357578
[Abstract]:Objective to study the difference between cognitive function and normal control in patients with acute isolated brainstem stroke, and to explore the effect of brainstem stroke on cognitive function and its main impaired cognitive domain. Methods A total of 29 patients with acute isolated brainstem stroke and 20 normal controls who matched sex, age and years of education were selected to perform ACE- 鈪,
本文編號:2357578
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