【摘要】：目的調(diào)查卒中后抑郁(PSD)發(fā)病的民族差異性,為臨床PSD的早期干預提供指導依據(jù)。方法以2014年1月-2015年9月間在新疆石河子大學醫(yī)學院第一附屬醫(yī)院及新疆維吾爾自治區(qū)中醫(yī)醫(yī)院收治的624名腦卒中患者為研究對象。將出院后1周符合PSD診斷的分為PSD組,不符合的分為非PSD組。應用χ~2檢驗比較不同民族PSD發(fā)生率的差異;應用Logistic回歸模型,控制社會人口學變量及疾病相關變量的影響后,分析民族對PSD發(fā)病的影響。結(jié)果 (1)漢族PSD發(fā)生率為31.2%、維吾爾族PSD發(fā)生率為19.0%、哈薩克族PSD發(fā)生率為14.2%,3個民族PSD發(fā)生率差異有統(tǒng)計學意義(χ~2=18.259,P=0.001)。(2)在扣除了其他因素的影響后,維吾爾族發(fā)生PSD的風險是漢族的0.392倍(OR=0.392,95%CI:0.243~0.634,P=0.001),哈薩克族發(fā)生PSD的風險是漢族的0.290倍(OR=0.290,95%CI:0.162~0.518,P=0.001)。結(jié)論相比于漢族,維吾爾族與哈薩克族是PSD的保護因素,建議未來的研究設置較長的隨訪期對本研究的結(jié)論進行驗證。
[Abstract]:Objective to investigate the national differences of (PSD) in post-stroke depression and to provide guidance for early intervention of PSD. Methods from January 2014 to September 2015, 624 stroke patients were treated in the first affiliated Hospital of Medical College of Shihezi University of Xinjiang and Chinese Medicine Hospital of Xinjiang Uygur Autonomous region. One week after discharge, those who met PSD diagnosis were divided into PSD group and non-PSD group. 蠂 ~ 2 test was used to compare the incidence of PSD among different nationalities, and Logistic regression model was used to analyze the influence of ethnic groups on the incidence of PSD after controlling the influence of social demographic variables and disease-related variables. Results (1) the incidence of PSD in Han nationality was 31.2%, the incidence rate of PSD in Uygur nationality was 19.0, the incidence rate of PSD in Kazak nationality was 14.22.There was significant difference in the incidence of PSD among the three nationalities (蠂 ~ 2 ~ 18.259, 蠂 ~ 2 = 18.259, P < 0.01). After deducting the influence of other factors, Uygur people were 0.392 times more likely to develop PSD than the Han nationality (OR=0.392,95%CI:0.243~0.634,P=0.001). The Kazakh population is 0.290 times more OR=0.290,95%CI:0.162~0.518,P=0.001 at risk of PSD than the Han nationality. Conclusion compared with the Han nationality, Uygur and Kazak are the protective factors of PSD. It is suggested that the future study should be followed up for a longer period to verify the conclusion of this study.
【作者單位】： 石河子大學醫(yī)學院第一附屬醫(yī)院康復心理科;石河子大學醫(yī)學院第一附屬醫(yī)院神經(jīng)內(nèi)科;新疆維吾爾自治區(qū)中醫(yī)醫(yī)院推拿科;
【基金】：院級科研項目(YL2015R0067)
【分類號】：R743.3;R749.4

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