老年精神分裂癥患者前瞻性記憶的損傷階段初探
[Abstract]:Objective: to investigate the stage of event-based prospective memory (EBPM) and time-based prospective memory (TBPM) in elderly schizophrenics. Methods: Forty-one inpatients with senile schizophrenia in accordance with the fourth edition of the American Diagnostic and Statistical Manual for Mental Disorders and 55 normal controls with matched ages and educational attainment were selected. A prospective memory laboratory model was developed to evaluate the total score and internal scores of EBPM. The psychiatric and negative symptoms of patients were evaluated by (BPRS) and (BNSS). Continuous attention test (CPT) was used to evaluate the discrimination of signal / noise, and Wisconsin Card sorting Test (WCST) and semantic fluency (CF) (CF) were used to evaluate the executive function of the subjects, and the number of complete classification and correct response were recorded respectively. Results: the scores of EBPM [4 (0 8) vs.6 (0 8) P 0.01] and TBPM [2 (0 8) vs.6 (0 0 8) P 0 01] in schizophrenia group were lower than those in control group, the task replacement score of EBPM [2 (0 8) vs.1 (0 8) P 0 05] in schizophrenia group and the missing score of TBPM task [2 (0 8) vs.0 (0 0 6) P 0. 01] were significantly lower in schizophrenia group than those in control group [7 (0 7) vs.7 (57) P 0. 01]. In addition, the retrospective recognition score of TBPM in schizophrenia group was significantly lower than that in control group [7 (0 7) vs.7 (57) P 0. 01]. Conclusion: both EBPM and TBPM were significantly damaged in senile schizophrenic patients, and the main damage stage was self-priming cues and intention extraction. In addition, TBPM may also be damaged during the maintenance phase.
【作者單位】: 北京大學(xué)北京回龍觀醫(yī)院;
【基金】:首都醫(yī)學(xué)發(fā)展科研基金項(xiàng)目(計(jì)算機(jī)認(rèn)知矯正治療對(duì)老年輕度認(rèn)知障礙的干預(yù)研究,2009-1056) 北京市衛(wèi)生系統(tǒng)高層次衛(wèi)生技術(shù)人才培養(yǎng)計(jì)劃(神經(jīng)免疫自由基,2011-3-077)
【分類(lèi)號(hào)】:R749.3
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