【摘要】：目的探討蒙特利爾認(rèn)知評(píng)估量表（Montrealcognitiveassessment,MoCA）在篩查血管性認(rèn)知功能障礙患者的應(yīng)用，同時(shí)與簡(jiǎn)易精神狀態(tài)量表（Mini-MentalStateExamination，MMSE）進(jìn)行比較研究。 方法通過將研究對(duì)象分為寧夏醫(yī)科大學(xué)附屬醫(yī)院住院及門診VCIND患者58例為病例組，以及健康體檢者62例為對(duì)照組。通過MoCA量表及MMSE量表，評(píng)價(jià)其認(rèn)知功能水平，統(tǒng)計(jì)MoCA量表與MMSE的相關(guān)性，并通過繪制ROC曲線以及敏感度和特異度的統(tǒng)計(jì)分析，找出篩查VCI的最佳分界值。 結(jié)果MoCA量表在篩查工作中表現(xiàn)出與MMSE量表良好的相關(guān)性(r＞0.8)，原26分正常分界值篩查敏感度及特異度為96.55%和80.42%。通過MoCA量表各分值對(duì)應(yīng)的敏感度及特異度繪制ROC曲線，發(fā)現(xiàn)曲線下面積（AUC）=0.985，，MMSE量表的曲線下面積為0.841。MoCA量表分界值設(shè)置在24分時(shí)，敏感度及特異度為93.10%與89.87%，所對(duì)應(yīng)的約登指數(shù)為所有分值對(duì)應(yīng)的最大值（YI=0.899）。 結(jié)論（1）MoCA量表操作簡(jiǎn)單，被檢測(cè)者依從性好，臨床使用可操作性強(qiáng)。（2）MoCA量表與MMSE量表評(píng)測(cè)分值具有良好相關(guān)性，可以反映被測(cè)試者的認(rèn)知功能情況。（3）MoCA量表正常分界值用于篩查VCI患者可能過高，將正常分界值設(shè)置在24分時(shí)篩查VCI患者更為理想（。4）MMSE量表篩查VCI患者存在敏感度過低的情況，在篩查VCI患者的應(yīng)用中，MoCA量表要優(yōu)于MMSE量表。
[Abstract]:Objective to investigate the application of Montreal Cognitive Assessment scale (MOCA) in screening patients with vascular cognitive impairment and to compare it with Mini-MentalStateExaminationMMSE (Mini-MentalStateExaminationMMSE). Methods the subjects were divided into two groups: 58 inpatients and outpatients with VCIND in affiliated Hospital of Ningxia Medical University, and 62 healthy persons as control group. The cognitive function of MoCA and MMSE were evaluated, and the correlation between MoCA and MMSE was analyzed. The best threshold of VCI screening was found by drawing ROC curve and statistical analysis of sensitivity and specificity. Results the MoCA scale showed a good correlation with MMSE scale (r > 0. 8). The sensitivity and specificity of normal threshold of 26 scores were 96.55% and 80.42% respectively. The sensitivity and specificity of each score of MoCA scale were used to draw the ROC curve. It was found that the area under the curve area of (AUC) 0.985 MMSE scale was when the threshold of 0.841.MoCA scale was set at 24 points. The sensitivity and specificity were 93.10% and 89.87% respectively. The corresponding Jordan index was the maximum value (YI=0.899) of all the scores. Conclusion (1) the MoCA scale is simple in operation, good in compliance and maneuverability in clinical use. (2) there is a good correlation between the MoCA scale and the evaluation score of MMSE scale. It can reflect the cognitive function of the subjects. (3) the normal threshold value of MoCA scale may be too high for screening patients with VCI. It is more ideal to screen VCI patients with normal threshold value at 24 minutes. (.4) there is a low sensitivity in the screening of VCI patients with MMSE scale. In screening for VCI patients, the MoCA scale was superior to the MMSE scale.
【學(xué)位授予單位】：寧夏醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R749.1

【參考文獻(xiàn)】

相關(guān)期刊論文 前9條

1 賈功偉;宋琦;殷櫻;趙紅霞;王令;趙若谷;許川山;虞樂華;;蒙特利爾認(rèn)知評(píng)估量表在重慶地區(qū)應(yīng)用的初步研究[J];神經(jīng)損傷與功能重建;2008年01期

2 張磊;章軍建;;血管性認(rèn)知障礙研究進(jìn)展[J];中國(guó)臨床神經(jīng)科學(xué);2008年06期

3 張振馨,ZahnerGE,RomanGC,劉君,洪震,屈秋民,劉協(xié)和,張曉君,周玢,武成斌,唐牟尼,洪霞,李輝;中國(guó)北京、西安、上海和成都地區(qū)癡呆亞型患病率的研究[J];中國(guó)現(xiàn)代神經(jīng)疾病雜志;2005年03期

4 賈功偉;殷櫻;虞樂華;宋琦;;蒙特利爾認(rèn)知評(píng)估量表與簡(jiǎn)易精神狀態(tài)檢查用于評(píng)定阿爾茨海默病患者認(rèn)知功能的比較[J];中國(guó)康復(fù)醫(yī)學(xué)雜志;2010年04期

5 張彥紅;梁偉雄;朱磊;尤勁松;;蒙特利爾認(rèn)知評(píng)估量表與簡(jiǎn)易精神狀態(tài)量表用于篩查血管性認(rèn)知障礙的比較[J];中國(guó)康復(fù)醫(yī)學(xué)雜志;2012年05期

6 賈建平,魏翠柏;血管性認(rèn)知障礙提出的臨床意義[J];中華老年醫(yī)學(xué)雜志;2005年01期

7 賈建平;重視血管性認(rèn)知障礙的早期診斷和干預(yù)[J];中華神經(jīng)科雜志;2005年01期

8 靳慧;丁斌蓉;楊霞;雷曾輝;曾湘良;白松;唐湘祁;涂秋云;;北京版MoCA在長(zhǎng)沙地區(qū)缺血性腦血管病人群中的應(yīng)用及長(zhǎng)沙版MoCA的形成[J];中國(guó)神經(jīng)精神疾病雜志;2011年06期

9 張立秀;劉雪琴;;蒙特利爾認(rèn)知評(píng)估量表中文版廣州市老人院人群劃界分探討[J];中國(guó)心理衛(wèi)生雜志;2008年02期

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