本文選題：抽動障礙 + 生活質量�。� 參考：《大連醫(yī)科大學》2012年碩士論文

【摘要】：目的：評估抽動障礙（TD）兒童的生活質量；分析不同臨床狀況下TD兒童的生活質量狀況；探討影響抽動障礙兒童生活質量的因素。 方法：TD組72例（包括單純TD組48例，TD+ADHD組24例），對照組47例。所有被試者完成一般情況調查表、兒少主觀生活質量問卷(ISLQ)、Achenbach兒童行為量表（CBCL，家長用）。采用卡方檢驗、t檢驗、單因素方差分析(ANOVA)、Kruskal-Wallis H檢驗、Pearson/Spearman相關性分析、多重線性回歸分析等方法，應用SPSS18.0軟件完成數(shù)據(jù)統(tǒng)計。 結果：①TD組的學校生活、焦慮體驗、軀體情感、認知成份、情緒成份及總體滿意度的得分明顯低于對照組，差異有統(tǒng)計學意義（P㩳0.05）。②TD組男童學校生活、認知成份得分低于TD組女童，差異有統(tǒng)計學意義（P㩳0.05），，TD組女童的焦慮體驗低于TD組男童，差異有統(tǒng)計學意義（P0.05）。③單純TD組、TD+ADHD組、正常組兒童的生活質量總體比較在焦慮體驗、認知成份、情緒成份及總體滿意度方面有差異（P＜0.05），兩兩比較顯示，TD+ADHD組的總體滿意度低于單純TD組，差異有統(tǒng)計學意義（P㩳0.05）。④不同臨床類型、不同嚴重程度的TD兒童生活質量的各維度、成份及總體滿意度得分比較，差異無統(tǒng)計學意義（P＞0.05）。⑤年齡與軀體情感負相關；病程與學校生活負相關；內向性行為問題與家庭生活、學校生活、生活環(huán)境、抑郁體驗、認知成份、情緒成份、總體滿意度負相關；外向性行為問題與生活環(huán)境、情緒成份及總體滿意度負相關；行為問題總分與學校生活、生活環(huán)境、抑郁體驗、焦慮體驗、情緒成份及總體滿意度負相關。⑥多重線性回歸顯示：影響TD兒童生活質量的主要因素是內向性行為問題和是否共患ADHD，TD兒童生活質量與內向性行為問題及是否共患ADHD呈負相關。 結論：①TD兒童生活質量的部分維度、認知和情緒成份及總體滿意度較正常兒童降低，不同性別、是否共患ADHD其生活質量各不相同，不同臨床類型、不同嚴重程度的生活質量未見差異。②抽動障礙兒童的行為問題與生活質量的諸多維度、認知、情緒及總體滿意度有關聯(lián)。③內向性行為問題、共患ADHD是影響抽動障礙兒童生活質量的主要因素。
[Abstract]:Objective: to evaluate the quality of life (QOL) of children with tic disorder (TD), to analyze the quality of life (QOL) of children with tic disorder (TD) under different clinical conditions, and to explore the factors affecting the QOL of children with THD. Methods A total of 72 cases (including 48 cases of TD group and 24 cases of TD ADHD group) and 47 cases of control group were divided into two groups. All subjects completed the General situation questionnaire and the Children's subjective quality of Life questionnaire (ISLQ) and the Achenbach Children's behavior scale (CBCLs). By means of chi-square test / t test, single factor variance analysis (ANOVA) / Kruskal-Wallis H test Pearson / Spearman correlation analysis and multiple linear regression analysis, SPSS 18.0 software was used to complete the data statistics. Results the scores of school life, anxiety experience, somatic emotion, cognitive component, emotional composition and overall satisfaction in the group of 1: 1TD were significantly lower than those in the control group (P0. 05) .2TD group, the scores of school life of boys were significantly lower than those of the control group (P0. 05). The scores of cognitive components in TD group were lower than those in TD group (P 0.05). The anxiety experience of TD group was lower than that of TD group (P0.05). The difference was statistically significant (P0.05). 3. The quality of life of children in normal group was compared with that of TD ADHD group (P0.05). There were significant differences in cognitive, emotional and total satisfaction (P < 0.05). The total satisfaction of TD ADHD group was lower than that of TD group (P < 0.05), and the difference was statistically significant (P < 0.05). The scores of quality of life, composition and overall satisfaction of children with different severity of TD were not significantly different (P > 0.05). 5 age was negatively correlated with somatic emotion, course of disease was negatively correlated with school life. Introverted behavior problems were negatively correlated with family life, school life, living environment, depression experience, cognitive component, emotional component, total satisfaction, extroverted behavior problems were negatively correlated with living environment, emotional composition and overall satisfaction. The total score of behavioral problems and school life, living environment, depression experience, anxiety experience, There was a negative correlation between emotional components and overall satisfaction. 6 multiple linear regression showed that introverted behavior problems and coexisting ADHD TD children had negative correlation with introverted behavior problems and coexisting ADHD. 6 multiple linear regression showed that introverted behavior problems and coexisting ADHD were the main factors affecting children's quality of life (QOL) in TD children. Conclusion part of dimension of quality of life, cognitive and emotional components and overall satisfaction of children with 1: 1TD were lower than those of normal children. There was no difference in the quality of life of children with different severity. 2 there was no difference between behavioral problems in children with tic disorder and many dimensions of quality of life, cognition, emotion and overall satisfaction. 3. Introverted behavior problems were found in children with tic disorders. Coexisting ADHD is a major factor affecting the quality of life of children with tic disorder.
【學位授予單位】：大連醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2012
【分類號】：R749.94

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