發(fā)布時(shí)間：2018-06-04 12:25

  本文選題：心房顫動(dòng) + 認(rèn)知功能障礙　； 參考：《蘭州大學(xué)》2017年碩士論文

【摘要】：目的:心房顫動(dòng)是老年人中最為常見的心律失常,隨著人口老齡化不斷加速,高血壓、糖尿病、冠心病等心血管相關(guān)疾病的患病率不斷增加,房顫的發(fā)病率在全球范圍內(nèi)呈升高趨勢(shì)。許多國(guó)外研究表明,房顫可以導(dǎo)致非卒中性認(rèn)知功能障礙并可加速認(rèn)知功能進(jìn)一步惡化,認(rèn)知功能障礙導(dǎo)致個(gè)人生活質(zhì)量的下降、家庭和社會(huì)的經(jīng)濟(jì)負(fù)擔(dān)加重,成為人們逐漸關(guān)注的焦點(diǎn)。因此本研究通過(guò)對(duì)房顫及非房顫患者進(jìn)行一般資料的統(tǒng)計(jì)及MMSE、MoCA量表認(rèn)知功能評(píng)價(jià),探討房顫與非卒中性認(rèn)知功能障礙的相關(guān)性。方法:本研究以2015年4月-2016年10月就診于蘭州大學(xué)第二醫(yī)院心內(nèi)科的非卒中房顫患者共99名設(shè)為病例組,以房顫患者性別、年齡、受教育程度為匹配因素納入99名非房顫患者作為對(duì)照組,記錄患者一般資料、統(tǒng)計(jì)患者輔助檢查結(jié)果,通過(guò)MMSE及MoCA量表對(duì)兩組患者進(jìn)行認(rèn)知功能評(píng)價(jià),比較兩組患者認(rèn)知功能障礙的患病情況。結(jié)果:1)通過(guò)MMSE量表評(píng)估,病例組患者存在認(rèn)知功能障礙30人(30.3%),對(duì)照組患者存在認(rèn)知功能障礙者18人(18.2%),兩組通過(guò)配對(duì)卡方檢驗(yàn)示,P0.001,兩組差異有統(tǒng)計(jì)學(xué)意義。2)通過(guò)MoCA量表評(píng)估,病例組患者中存在認(rèn)知障礙者90人(90.9%),對(duì)照組患者中存在認(rèn)知障礙者73人(73.7%),P0.001,兩組差異有統(tǒng)計(jì)學(xué)意義。兩種量表檢查均提示病例組中認(rèn)知功能障礙的患病率較高。結(jié)論房顫是導(dǎo)致非卒中性認(rèn)知功能障礙的獨(dú)立危險(xiǎn)因素。
[Abstract]:Objective: atrial fibrillation is the most common arrhythmia in the elderly, and the prevalence of cardiovascular diseases such as hypertension, diabetes, coronary heart disease and so on increases with the aging of the population. The incidence of atrial fibrillation is increasing worldwide. Many foreign studies have shown that atrial fibrillation can lead to non-stroke neutral cognitive dysfunction and accelerate the further deterioration of cognitive function, cognitive dysfunction leads to a decline in personal quality of life, family and social economic burden. Become the focus that people pay attention to gradually. Therefore, this study investigated the correlation between atrial fibrillation and non-stroke neutral cognitive dysfunction by statistical analysis of general data and evaluation of cognitive function of MMSE MoCA scale in patients with atrial fibrillation and non-atrial fibrillation. Methods: from April 2015 to October 2016, 99 patients with non-apoplectic atrial fibrillation in Department of Cardiology, second Hospital of Lanzhou University were selected as the case group. The educational level was matched by 99 non-atrial fibrillation patients as the control group. The general data of the patients were recorded and the results of auxiliary examination were counted. The cognitive function of the two groups was evaluated by MMSE and MoCA scale. To compare the prevalence of cognitive dysfunction between the two groups. Results according to the MMSE scale, 30 patients with cognitive dysfunction in the case group and 18 patients with cognitive dysfunction in the control group were assessed by MoCA scale. The matched chi-square test showed P 0.001. The difference between the two groups was statistically significant. 90 patients with cognitive impairment in the case group and 73 patients with cognitive impairment in the control group had cognitive impairment (P 0.001). The difference between the two groups was statistically significant. The prevalence of cognitive impairment was higher in the two scales. Conclusion Atrial fibrillation is an independent risk factor for non-apoplectic cognitive impairment.
【學(xué)位授予單位】：蘭州大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R541.75;R749.1

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本文編號(hào)：1977346